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UTP regulation of ion transport in alveolar epithelial cells involves distinct mechanisms
Lung Cellular and Molecular Physiology, 06/23/09
Yang C et al. - The results suggest that UTP induces opposite changes in Isc in AEC I and AEC II, likely due to the reversed Cl- flux and different contribution of ENaC and IKCa. These results further imply a new concept that type II cells contribute to UTP-induced fluid secretion and type I cells contribute to UTP-induced fluid absorption in alveoli.
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