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Khemani RG et al. - At least 30% of children in a cross section of United States PICUs are endotracheally intubated, and 25% of patients with respiratory failure do not fulfill radiographic criteria for ALI. While few patients without an indwelling arterial line require more than modest ventilator support, many may still meet oxygenation criteria for ALI. These findings will facilitate sample size calculations and help determine feasibility for future trials on pediatric mechanical ventilation.

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