Your Messages Inbox
Most Viewed Abstracts
1. Report Shows Shift in Starting Salaries for Physicians 2. 2008 Exclusive Survey—Earnings: Good news for primary care income 3. Medicare pay-for-reporting effort draws fire from frustrated doctors 4. Debunking Myths in the US Healthcare System 5. EGFR inhibitors as first-line therapy in advanced non-small cell lung cancer
Your Article Summary
See Latest ArticlesDetection of bone metastases in patients with lung cancer: 99mTc-MDP planar bone scintigraphy, 18F-fluoride PET or 18F-FDG PET/CT
European Journal of Nuclear Medicine & Molecular Imaging, 06/09/09
Krüger S et al. - In a study to compare diagnostic accuracy of 18F-fluorodeoxyglucose (FDG) PET/CT vs standard planar bone scintigraphy (BS) and 18F-labelled NaF (18F) PET for detection of bone metastases (BM) in non-small cell lung cancer (NSCLC), it was concluded that integrated 18F-FDG PET/CT is superior to BS in detection of osteolytic BM in NSCLC. PET/CT may obviate the need to perform additional BS or 18F PET in staging of NSCLC, which significantly reduces costs.
Methods- 18F-FDG PET/CT was performed in 126 pts with NSCLC.
- Within 7 days BS (n=58) or 18F PET (n=68) was performed.
- 18F-FDG PET/CT, BS and 18F PET were evaluated by 2 experienced readers.
- Lesions were graded on a scale from 1 (definite BM) to 5 (degenerative lesion), and equivocal lesions were determined as indifferent (grade 3).
- 92 pts showed degenerative lesions (grade 4/5) on PET/CT, BS or 18F PET.
- In 34 pts (27%), BM lesions were diagnosed (grades 1 and 2).
- In 13 of 18 pts, BM were concordantly diagnosed with PET/CT and 18F PET.
- PET/CT showed more BM vs 18F PET (53 vs 40).
- In 1 pt, 1 osteolytic BM was false-negative on 18F PET.
- 18F PET identified 4 pts with BM compared with negative findings on PET/CT.
- Of 16 pts, 11 had concordant findings of BM on PET/CT and BS.
- In 3 pts, BS was false-negative and in 2 pts BM were diagnosed as indifferent.
Related Articles
Hodgkin's lymphoma in remission after first-line therapy: Which patients need FDG-PET/CT for follow-up?
Annals of Oncology, 11/17/09
Relevance Score: 70%
Evaluation of gross tumor size using CT, 18F-FDG PET, integrated 18F-FDG PET/CT and pathological analysis in non-small cell lung cancer
European Journal of Radiology, 10/26/09
Relevance Score: 69%
Incidental Detection of Granulomatous Prostatitis by F-18 FDG PET/CT in a Patient with Bladder Cancer: A Rare Complication of BCG Instillation Therapy
Clinical Nuclear Medicine, 10/07/09
Relevance Score: 68%
FDG Uptake in a Rheumatoid Nodule With Imaging Appearance Similar to a Malignant Soft Tissue Tumor
Clinical Nuclear Medicine, 10/07/09
Relevance Score: 67%
Intraspinal Canal Neurolymphomatosis Detected by FDG-PET/CT
Clinical Nuclear Medicine, 10/07/09
Relevance Score: 67%
Today in Diagnostic/Lung Function...keeping you current
Receive free subspecialty "5-minute updates" via email
Volumetric or time-based capnography for excluding pulmonary embolism in outpatients
Journal of Thrombosis and Haemostasis, 12/18/09
Development of the Lung Function Questionnaire (LFQ) to identify airflow obstruction
International Journal of COPD, 12/18/09
Multiple cavitating nodules in a renal transplant recipient
Canadian Respiratory Journal, 12/18/09
Today in Lung/Thoracic Oncology...keeping you current
Receive free subspecialty "5-minute updates" via email
Pain in patients with lung cancer: Pathophysiology and treatment
Lung Cancer, 12/18/09
Taurolidine in the prevention and therapy of lung metastases
European Journal of Cardio-Thoracic Surgery, 12/18/09
A small-cell lung cancer genome with complex signatures of tobacco exposure
Nature, 12/18/09
Sponsor
Article Search
Sponsor
Sponsor