Pulmonology

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Toll-like Receptor (TLR)-4 Mediated Innate Immunity is Reduced in Cystic Fibrosis Airway Cells
American Journal of Respiratory Cell and Molecular Biology, 06/09/09

John G et al. - In histological lung sections of CF patients the TLR-4 expression in the bronchial epithelium was significantly reduced compared to healthy control subjects. In CF the loss of CFTR function appears to decrease innate immune responses, possibly by altering the expression of TLR-4 on airway epithelial cells. This may contribute to chronic bacterial infection of CF airways.

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Cisplatin-induced expression of Gb3 enables verotoxin-1 treatment of cisplatin resistance in malignant pleural mesothelioma cells
British Journal of Cancer, 12/18/09

Increase in Passive Stiffness at Reduced Airway Smooth Muscle Length: Potential Impact on Airway Responsiveness
Lung Cellular and Molecular Physiology, 12/18/09

Modulation of epithelial sodium channel activity by lipopolysaccharide in alveolar type II cells: Involvement of purinergic signaling
Lung Cellular and Molecular Physiology, 12/18/09

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Today in Cystic Fibrosis...keeping you current

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Prognostic Factors in Idiopathic Pulmonary Fibrosis
The American Journal of the Medical Sciences, 12/17/09

Modulation of endocytic trafficking and apical stability of CFTR in primary human airway epithelial cultures
Lung Cellular and Molecular Physiology, 12/16/09

Influenza Associated Cystic Fibrosis Pulmonary Exacerbations
Chest, 12/14/09

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