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Mycobacterium tuberculosis in Ontario, Canada: Insights from IS6110 RFLP and MIRU–VNTR Genotyping
Journal of Clinical Microbiology, 06/04/09
Alexander DC et al. - A collection of 1308 clinical Mycobacterium tuberculosis isolates from Ontario, Canada was genotyped by IS6110 RFLP and MIRU-VNTR. RFLP or >12 MIRU-VNTR loci were necessary for resolution of Indo-Oceanic strains. The low clustering rate and high strain diversity indicate that, in Ontario, most tuberculosis results from reactivation of latent infections.
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