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See Latest ArticlesTiotropium induced bronchodilation and protection from dynamic hyperinflation is independent of extent of emphysema in COPD
Pulmonary Pharmacology and Therapeutics, 05/13/09
Gelb AF et al. - Tiotropium significantly increased FEV1 (L) and inspiratory capacity in moderate-severe COPD, independent of extent of lung CT emphysema score. Despite bronchodilation and lower resting lung volume, tiotropium did not abbreviate induced dynamic hyperinflation, which was also independent of underlying emphysema.
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