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See Latest ArticlesT Cells Subtypes in a Patient With Interferon-[alpha] Induced Sarcoidosis
The American Journal of the Medical Sciences, 01/28/09
Monsuez JJ et al. - It was marked by a mild increase in activated cells (expressing R-IL2 and HLADR), and a markedly reduced percentage of CD4 T cells expressing the costimulation molecule CD28, ie, an expansion of the CD4+CD28 negative subset that is associated with proinflammatory and tissue damaging properties. This activation process also improved over time, but more slowly than clinical symptoms.
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