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Capdevila AA et al. - Smoke inhalation injury can be considered as a systemic disease. Early mortality and systemic involvement are due to the severity of thermal injury of the upper airway and to CO poisoning associated with other combustion materials. Bronchoscopy is useful in identifying severity of airway injury and performing bronchial toilet and BAL culture, thus allowing early diagnosis of pulmonary infections and the adjustment of antibiotic treatment. Corticosteroid therapy should be considered when persistent acute respiratory distress syndrome, interstitial pneumonia, or obliterans bronchiolitis is suspected without evidence of active infection. Obstruction airway disease can persist several months after the smoke inhalation.

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