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Lee JC et al. - This article will review this definition and issues surrounding it, outcome studies examining the long-term effects of PGD, and the established clinical risk factors for PGD. Translational studies exploring the pathogenesis of PGD will be highlighted, and the current state of PGD prevention and management will also be described. Finally, the authors will summarize efforts at finding genetic and molecular markers for PGD and discuss future directions for PGD research.

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