Nitric oxide mediates lung vascular permeability and lymph-borne il-6 after an intestinal ischemic insult
Breithaupt-Faloppa AC et al. - Intestinal ischemia and absence of constitutive NOS activity leading to additional intestinal stress both cause release of IL-6 and increase of lung microvascular permeability. Because anti-IL-6 prevented the endothelial cell injury caused by lymph at the ischemia period, the lymph-borne IL-6 might be involved with endothelial cell activation. At the reperfusion period, this cytokine does not seem to be modulated by NO. [more...]
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