Top obesity Articles in Pulmonology

Amylin Pharmaceuticals Highlights New Data Supporting Therapeutic Potential of Obesity Pipeline at Obesity 2009
Amylin Pharmaceuticals, 10/20/2009

Amylin Pharmaceuticals, Inc. announced that new data from its obesity program will be presented at Obesity 2009, the 27th Annual Scientific Meeting of The Obesity Society, to be held in Washington, D.C. October. Phase 2 ... combination treatment clinical program will be the subject of a late–breaking oral presentation. Obesity 2009 is one of the largest scientific conferences in the field of obesity. [more...]

Obesity, intentional weight loss and physical disability in older adults
Obesity Reviews, 11/18/2009

Rejeski WJ et al. – Based on prospective epidemiological studies, body mass index exhibits a curvilinear relationship with physical disability; there appears to be some protective effect associated with older adults ... obesity, the effects of obesity on physical disability appears to be moderated by both sex and race. Obesity at age 30 years constitutes a greater risk for disability later in life than when obesity develops at age 50 years or later; however, physical activity may buffer the adverse effects obesity ... beneficial in these programmes as this mode of exercise attenuates the loss of fat–free mass during caloric restriction. [more...]

Early life influences on obesity risk: maternal overnutrition and programming of obesity
Expert Review of Endocrinology & Metabolism, 11/12/2009

Morris MJ – This review summarizes recent evidence of the impact of maternal obesity on subsequent obesity risk, paying particular attention to the hypothalamic regulation of appetite and markers of ... rise in the rates of maternal obesity underlines an urgent need to investigate the mechanisms contributing to its transgenerational effects. [more...]

Obesity as a disease state: A new paradigm for diagnosis and treatment
Clinical Cornerstone, 10/21/2009

Aronne LJ et al. – The etiology of obesity is multifactorial, ranging from lifestyle choices such as excess food intake and insufficient physical activity, to use of medications that have weight gain as an undesirable ... even social networks may also contribute to obesity. Successful management of obesity requires the understanding and acceptance of a new paradigm that identifies obesity as a disease—one defined by waist circumference—that requires treatment. Obesity meets all accepted criteria of a medical disease ... Excess adipose tissue acts as an endocrine organ to produce excess free fatty acids, as well as tumor necrosis factor–alpha, interleukin–6, leptin, and plasminogen activator inhibitor–1. [more...]

Obesity as a Social Problem in the United States
Policy, Politics, & Nursing Practice, 10/01/2009

Smith MC – This article applies Hilgartner and Bosk’s public arenas model to examine how obesity is defined in the public arena, how competition plays a role in "framing" the obesity issue, and how operatives influence the ways in which ... obesity is viewed and understood. Implications for nurses and policy makers are addressed in the context of using the public arenas model as a tool to analyze the social problem of obesity. [more...]

Obesity indicators and cardiometabolic status in 4-y-old children
American Journal of Clinical Nutrition, 11/19/2009

Corvalan C et al. – Obesity and central obesity were common, and most of the children had at least one cardiometabolic risk factor, particularly lipid disorders. Obesity and central obesity indicators were highly ... related to cardiometabolic status. At this age, body mass index and waist circumference were poor predictors of cardiometabolic status. [more...]

Obesity and Alzheimer’s Disease: A Link Between Body Weight and Cognitive Function in Old Age
American Journal of Alzheimer's Disease and Other Dementias, 10/07/2009

Naderali EK et al. – Obesity is now a global health hazard. It not only predisposes to an array of risk factors leading to increased morbidity and mortality amongst adults but it also has a major ... children’s health. The deleterious effects of obesity on cardiovascular system have now been well acknowledged. It causes insulin resistance that in turn leads to diabetes, hypertension and cardiovascular abnormalities. The vascular effects of obesity may have a role in the development of a rapidly ... negative impact of obesity on cognitive function may be, at least in part, due to vascular defects, impaired insulin metabolism and signaling pathway or a defect in glucose transport mechanisms in brain. This review examines the available data regarding the impact of obesity on cognitive function ... alzheimer disease obesity, morbid [more...]

Changes in the Regional Prevalence of Child Obesity in 4th, 8th, and 11th Grade Students in Texas From 2000–2002 to 2004–2005
Obesity, 10/09/2009

Hoelscher DM et al. – The reduction of child obesity levels observed in the El Paso area is one of the few examples of effective programs and policies based on a ... extensive regional implementation of community programs for obesity prevention. Results emphasize the need for sustained school, community, and policy efforts, and that these efforts can result in decreases in child obesity at the population level. [more...]

Effects of maternal obesity on fetal growth and body composition: implications for programming and future health
Seminars in Fetal and Neonatal Medicine, 10/27/2009

Freeman DJ et al. – The review discusses the ideas contributing to the current working concept of obesity programming, and discusses several potential mechanisms that may underlie obesity programming ... and susceptibility to future metabolic and vascular disease. [more...]

Inflammation and impaired adipogenesis in hypertrophic obesity in man
Endocrinology and Metabolism, 10/30/2009

Gustafson B et al. – Understanding the molecular mechanisms for the impaired preadipocyte differentiation in the subcutaneous adipose tissue in hypertrophic obesity is a priority since it may lead to new ways of treating obesity and its associated metabolic ... basic science/genetics,obesity [more...]