Pulmonology - Clinical Pharmacology News & Articles

Are you looking to stay current with all of the latest Pulmonology news articles and research? Look no further! MDLinx Pulmonology medical editors extensively research respiratory medical journals to find the most beneficial Pulmonology clinical literature. Topics range from: Pediatric Pulmonology, Sleep Disorders, Asthma, COPD, Cystic Fibrosis and much more. In a matter of minutes, Pulmonologists and their staff can stay up to date with the most current published information.

On this page, you'll also find MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD. We also feature clinical pearls from our Internal Medicine Physician Review. You can also get the latest updates on salary information, search available Pulmonology jobs, view upcoming Pulmonology and CME conferences and earn some extra cash by participating in Market Research opportunities.

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Articles

Latest (1) Full Text Articles (212) Focus on Pediatrics

Ranked, sorted, and summarized by MDLinx editors from the latest literature

Topics:

141 Can molecular methods detect 1% isoniazid resistance in Mycobacterium tuberculosis? Journal of Clinical Microbiology, March 8, 2013 Clinical Article

142 Assessing the effectiveness and safety of liposomal paclitaxel in combination with cisplatin as first-line chemotherapy for patients with advanced NSCLC with regional lymph-node metastasis: study protocol for a randomized controlled trial (PLC-GC trial) Full Text Trials, March 8, 2013

143 Adherence to Varenicline and Associated Smoking Cessation in a Community-Based Patient Setting Full Text Journal of Managed Care Pharmacy, March 7, 2013 Clinical Article

144 Trepopnea Due to Amiodarone-Induced Diffuse Alveolar Hemorrhage Full Text Respiratory Care, March 7, 2013

145 Safety and tolerability of the novel inhaled corticosteroid fluticasone furoate in combination with the {beta}2 agonist vilanterol administered once daily for 52weeks in patients ≥12years old with asthma: a randomised trial Thorax, March 6, 2013 Clinical Article

146 Expert opinion in biological therapy: update on developments in lung gene transfer Expert Opinion on Biological Therapy, March 6, 2013 Review Article Clinical Article

147 Smoking cessation and COPD European Respiratory Review, March 5, 2013 Review Article Clinical Article

148 Ivacaftor treatment in patients with cystic fibrosis and the G551D-CFTR mutation European Respiratory Review, March 4, 2013 Clinical Article

149 Pharmacological Characterization of GSK573719 (Umeclidinium): A Novel, Long-Acting, Inhaled Antagonist of the Muscarinic Cholinergic Receptors for Treatment of Pulmonary Diseases Journal of Pharmacology and Experimental Therapeutics, March 4, 2013 Clinical Article

150 Glucocorticoid insensitivity as a source of drug targets for respiratory disease Current Opinion in Pharmacology , March 4, 2013 Review Article

151 Inhaled corticosteroids and the increased risk of pneumonia Therapeutic Advances in Respiratory Disease, March 1, 2013 Clinical Article

152 Low Prostaglandin E2 and Cyclooxygenase Expression in Nasal Mucosa Fibroblasts of Aspirin-Intolerant Asthmatics Respirology, March 1, 2013 Clinical Article

153 Statin treatment and the risk of recurrent pulmonary embolism European Heart Journal, February 28, 2013 Clinical Article

154 Efavirenz, tenofovir and emtricitabine combined with first-line tuberculosis treatment in tuberculosis–HIV-coinfected Tanzanian patients: a pharmacokinetic and safety study Antiviral Therapy , February 27, 2013 Clinical Article

155 Successful Epoprostenol Withdrawal in Pulmonary Arterial Hypertension: Case Report and Literature Review Full Text Respiratory Care, February 26, 2013

156 Sildenafil to improve respiratory rehabilitation outcomes in COPD: a controlled trial European Respiratory Journal , February 25, 2013 Clinical Article

157 Budesonide Inhalation Suspension Versus Montelukast in Children Aged 2 to 4 Years with Mild Persistent Asthma The Journal of Allergy and Clinical Immunology: In Practice, February 22, 2013 Clinical Article

158 Use of Aerosolized Tissue Plasminogen Activator in the Treatment of Plastic Bronchitis Annals of Pharmacotherapy, February 22, 2013 Review Article

159 Particle size and small airway effects of mometasone furoate delivered by dry powder inhaler Allergy and Asthma Proceedings, February 22, 2013 Clinical Article

160 Bevacizumab Combined with Chemotherapy for Advanced Non-small Cell Lung Cancer: A meta-analysis Chinese Journal of Lung Cancer, February 21, 2013 Evidence Based Medicine Clinical Article

50 available pages First Previous 8 9 10 11 12 13 14 15 16 17 Next Last

Clinical Pearls in Pulmonology

Chloral hydrate is a sedative that might be used to promote sleep in your pediatric migraine patients.
Along with cough variant asthma and nasal disease, gastroesophageal reflux is considered one of three main causes of chronic cough.
Trazodone does not improve sleep for methadone-maintained persons with sleep disturbance.

» Test your knowledge. Take the Smartest Doc challenge today!

Highlights in Pulmonology

Simvastatin has a modest effect on Streptococcus pneumoniae infections

Using a murine mouse model of pneumonia, prolonged simvastatin therapy has a measureable effect on Streptococcus pneumoniae infection, but no effect on mortality. Mice were treated with simvastatin (1 mg/kg/d [low dose] or 10 mg/kg/d [high dose]) for 4 weeks, then infected with S. pneumoniae intrathecally. Mice treated with the high-dose regimen had less lung consolidation, decreased macrophage and neutrophil infiltration, decreased MCP-1, KC, and ICAM-1 production, and decreased bacterial titers in the blood 36 and 42 h post-infection. Despite these favorable physiologic effects, there was no effect on mortality compared to control mice treated with ampicillin 48 h post-infection.

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Low D-dimer levels identify low-risk patients with community-acquired pneumonia

As published in the European Journal of Internal Medicine, there were no mortalities in patients with community-acquired pneumonia (CAP) and low levels of D-dimer (< 500 ug/l). Of 147 patients in the study, D-dimer levels were elevated in those with severe CAP (2166 vs. 1630 ug/l), day 30-clinical failure (2228 vs. 1594 ug/l), early failure (2499 vs. 1669 ug/l), and non-survivors (3025 vs. 1680 ug/l). Importantly, D-dimer levels were not shown to be associated with clinical outcome based on multivariate analysis.

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Bacteremia increases mortality risk in pneumococcal pneumonia

As published in the Journal of Infection, 114 of 981 (11.6%) of patients with pneumococcal pneumonia were bacteremic. Risk factors for bacteremia included immunosuppressants, age < 65 years, and diabetes mellitus. Patients with pneumococcal pneumonia and bacteria were at increased risk for mortality (28.6% vs. 8.5%). The combination of bacteremia, cerebrovascular disease, and septic shock had a strong association with mortality in patients with pneumococcal pneumonia.

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Most Popular Pulmonology Articles

Last month's top read Top Articles of 2012

1 High-Dose N-Acetylcysteine in the Prevention of COPD Exacerbations: Rationale and Design of the PANTHEON Study COPD: Journal of Chronic Obstructive Pulmonary Disease, April 9, 2013

2 Inhaled Corticosteroids in Lung Diseases American Journal of Respiratory and Critical Care Medicine, April 18, 2013

3 Feasibility of adding everolimus to carboplatin and paclitaxel, with or without bevacizumab, for treatment-naive, advanced non-small cell lung cancer Investigational New Drugs, April 12, 2013

4 Novel Functional Imaging of Changes in Small Airways of Patients Treated with Extrafine Beclomethasone/Formoterol Respiration, April 12, 2013

5 Regular treatment with salmeterol and inhaled steroids for chronic asthma: serious adverse events Cochrane Reviews, April 2, 2013 Review Article

6 Impact of intranasal corticosteroids on asthma outcomes in allergic rhinitis: a meta-analysis Allergy, April 19, 2013

7 Ten years of tiotropium: clinical impact and patient perspectives International Journal of COPD, March 18, 2013 Free full text Review Article

8 Asthma medication delivery: Mists and myths Paediatric Respiratory Reviews, April 12, 2013

9 Effects of Omalizumab in Non-Atopic Asthma Journal of Asthma, March 25, 2013

10 Review: inhaled anticholinergics increase risk of major cardiovascular events in COPD Evidence-Based Medicine, May 8, 2009

11 Indacaterol on dyspnea in chronic obstructive pulmonary disease: a systematic review and meta-analysis of randomized placebo-controlled trials BMC Pulmonary Medicine, April 26, 2013 Free full text Evidence Based Medicine Review Article

12 Leukotriene Inhibitor Warning JAMA, July 23, 2009

13 Statin treatment and the risk of recurrent pulmonary embolism European Heart Journal, February 28, 2013

14 A phase I trial of pan-Bcl-2 antagonist obatoclax administered as a 3-h or a 24-h infusion in combination with carboplatin and etoposide in patients with extensive-stage small cell lung cancer British Journal of Cancer, February 15, 2012

15 Use of dexamethasone and prednisone in acute asthma exacerbations in pediatric patients Canadian Family Physician, July 16, 2009 Free full text
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16 Phase III study of pemetrexed plus carboplatin compared with etoposide plus carboplatin in chemotherapy-naive patients with extensive-stage small-cell lung cancer Journal of Clinical Oncology, September 4, 2009 Free full text

17 Efficacy of Corticosteroid Therapy in Severe Decompensation of Chronic Obstructive Pulmonary Disease Requiring Mechanical Ventilation American Journal of Therapeutics, February 1, 2013

18 Promising therapeutic effects of sodium tanshinone IIA sulfonate towards pulmonary arterial hypertension in patients Journal of Thoracic Disease, April 3, 2013 Free full text

19 Developmental Current and Future Therapy for Severe Asthma Inflammation & Allergy - Drug Targets, April 8, 2013

20 Addition of Theophylline or Increasing the Dose of Inhaled Corticosteroid in Symptomatic Asthma: A Meta-Analysis of Randomized Controlled Trials Yonsei Medical Journal, February 22, 2011 Free full text Evidence Based Medicine

Indexed Journals in Pulmonology: Chest, Thorax, American Journal of Respiratory and Critical Care Medicine more

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Pulmonology - Clinical Pharmacology News & Articles

Articles

Clinical Pearls in Pulmonology

Highlights in Pulmonology

Simvastatin has a modest effect on Streptococcus pneumoniae infections

Low D-dimer levels identify low-risk patients with community-acquired pneumonia

Bacteremia increases mortality risk in pneumococcal pneumonia

Most Popular Pulmonology Articles

Other Topics in Pulmonology