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Pulmonology - Cystic Fibrosis News & Articles

Are you looking to stay current with all of the latest Pulmonology news articles and research? Look no further! MDLinx Pulmonology medical editors extensively research respiratory medical journals to find the most beneficial Pulmonology clinical literature. Topics range from: Pediatric Pulmonology, Sleep Disorders, Asthma, COPD, Cystic Fibrosis and much more. In a matter of minutes, Pulmonologists and their staff can stay up to date with the most current published information.

On this page, you'll also find MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD. We also feature clinical pearls from our Internal Medicine Physician Review. You can also get the latest updates on salary information, search available Pulmonology jobs, view upcoming Pulmonology and CME conferences and earn some extra cash by participating in Market Research opportunities.

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Your Unread Messages in Pulmonology

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Articles

Latest Full Text Articles (79) Focus on Sarcoidosis
Ranked, sorted, and summarized by MDLinx editors from the latest literature
Topics:

1 Benefits of combining inspiratory muscle with ‘whole muscle’ training in children with cystic fibrosis: a randomised controlled trial British Journal of Sports Medicine, May 21, 2013    Evidence Based Medicine

2 Next generation diagnostics of cystic fibrosis and CFTR-related disorders by targeted multiplex high-coverage resequencing of CFTR Journal of Medical Genetics, May 21, 2013    Review Article

3 Macitentan for the treatment of idiopathic pulmonary fibrosis: the randomised controlled MUSIC trial European Respiratory Journal , May 20, 2013    Clinical Article

4 Aortopulmonary collateral flow in cystic fibrosis assessed with phase-contrast MRI Pediatric Radiology, May 17, 2013    Clinical Article

5 Mitochondrial OXPHOS function is unaffected by chronic azithromycin treatment Journal of Cystic Fibrosis, May 16, 2013    Clinical Article

6 Treatment of Idiopathic Pulmonary Fibrosis With Ambrisentan - A Parallel, Randomized Trial Annals of Internal Medicine, May 15, 2013    Clinical Article

7 Phenotyping adults with non-cystic fibrosis bronchiectasis: A prospective observational cohort study Respiratory Medicine, May 15, 2013    Clinical Article

8 Cystic fibrosis and fertility Current Opinion in Obstetrics and Gynecology, May 15, 2013    Clinical Article

9 Stunting is an independent predictor of mortality in patients with cystic fibrosis Clinical Nutrition, May 15, 2013    Review Article

10 Skin pretreatment with microneedles prior to pilocarpine iontophoresis increases sweat production Clinical Physiology and Functional Imaging, May 15, 2013    Clinical Article

11 Non-invasive ventilation for cystic fibrosis Cochrane Reviews, May 14, 2013    Evidence Based Medicine    Clinical Article

12 Cystic fibrosis in the era of genomic medicine Current Opinion in Pediatrics, May 14, 2013    Review Article

13 Comparison of Lung Clearance Index Measured During Helium Washin and Washout in Children With Cystic Fibrosis Pediatric Pulmonology, May 14, 2013    Clinical Article

14 Diagnosis and Management of Concomitant Cystic Fibrosis in Patients With Chronic Obstructive Pulmonary Disease Clinical Pulmonary Medicine, May 14, 2013

15 Angiotensin-Converting Enzyme (ACE) Gene Polymorphisms are Associated with Idiopathic Pulmonary Fibrosis Lung, May 13, 2013    Clinical Article

16 Clinical measures of disease in adult non-CF bronchiectasis correlate with airway microbiota composition Thorax, May 10, 2013    Clinical Article

17 Genetic background of idiopathic pulmonary fibrosis Expert Review of Molecular Diagnostics, May 10, 2013    Review Article

18 Vitamin K supplementation for cystic fibrosis Cochrane Reviews, May 9, 2013    Evidence Based Medicine    Clinical Article

19 Biomarkers from bronchoalveolar lavage fluid in systemic sclerosis patients with interstitial lung disease relate to severity of lung fibrosis Respiratory Medicine, May 9, 2013    Clinical Article

20 Nebuliser systems for drug delivery in cystic fibrosis Cochrane Reviews, May 9, 2013    Evidence Based Medicine    Clinical Article

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Clinical Pearls in Pulmonology

Highlights in Pulmonology

Simvastatin has a modest effect on Streptococcus pneumoniae infections

Using a murine mouse model of pneumonia, prolonged simvastatin therapy has a measureable effect on Streptococcus pneumoniae infection, but no effect on mortality. Mice were treated with simvastatin (1 mg/kg/d [low dose] or 10 mg/kg/d [high dose]) for 4 weeks, then infected with S. pneumoniae intrathecally. Mice treated with the high-dose regimen had less lung consolidation, decreased macrophage and neutrophil infiltration, decreased MCP-1, KC, and ICAM-1 production, and decreased bacterial titers in the blood 36 and 42 h post-infection. Despite these favorable physiologic effects, there was no effect on mortality compared to control mice treated with ampicillin 48 h post-infection.

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Low D-dimer levels identify low-risk patients with community-acquired pneumonia

As published in the European Journal of Internal Medicine, there were no mortalities in patients with community-acquired pneumonia (CAP) and low levels of D-dimer (< 500 ug/l). Of 147 patients in the study, D-dimer levels were elevated in those with severe CAP (2166 vs. 1630 ug/l), day 30-clinical failure (2228 vs. 1594 ug/l), early failure (2499 vs. 1669 ug/l), and non-survivors (3025 vs. 1680 ug/l). Importantly, D-dimer levels were not shown to be associated with clinical outcome based on multivariate analysis.

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Bacteremia increases mortality risk in pneumococcal pneumonia

As published in the Journal of Infection, 114 of 981 (11.6%) of patients with pneumococcal pneumonia were bacteremic. Risk factors for bacteremia included immunosuppressants, age < 65 years, and diabetes mellitus. Patients with pneumococcal pneumonia and bacteria were at increased risk for mortality (28.6% vs. 8.5%). The combination of bacteremia, cerebrovascular disease, and septic shock had a strong association with mortality in patients with pneumococcal pneumonia.

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