Eucapnic Voluntary Hyperventilation Is Superior to Methacholine Challenge Testing for Detecting Airway Hyperreactivity in Nonathletes
Journal of Asthma, 07/27/2012
Holley AB et al. – EIB is common in nonathletes with exercise–induced symptoms, and eucapnic voluntary hyperventilation (EVH) is the preferred test for this population. Clinical implications. EIB is common in nonathletes who exercise regularly. In this population, methacholine challenge testing (MCCT) will miss most patients with EIB, and MCCT and EVH show only poor–to–moderate correlation. Capsule summary: EVH has not been compared with MCCT in nonathletes without a diagnosis of asthma. The study shows that the two tests are complementary in this population, but EVH is positive more often.