Malignant Pleural Mesothelioma in a Patient with Systemic Sclerosis: The First Report
Singh N et al. – The authors describe a 58–year–old never–smoker female, previously diagnosed with limited cutaneous Systemic sclerosis (SSc), who presented with chest pain on the left side, dyspnea and circumferential nodular left pleural thickening. Fluorodeoxyglucose positron–emission tomography–computed tomography showed intense uptake in the thickened left pleura, mediastinal lymph nodes and left femur. Pleural fluid cytological examination along with nuclear and membranous positivity for Wilms tumor–1 antigen and epithelial membrane antigen on immunocytochemistry confirmed the diagnosis of Malignant pleural mesothelioma (MPM).