Caffeine relaxes smooth muscle through actin depolymerization
The American Journal of Physiology - Lung Cellular and Molecular Physiology, 06/21/2012
Tazzeo T et al. – The authors conclude that, in addition to its other non–RyR targets, caffeine also interferes with actin function, an effect which should be borne in mind in studies using caffeine to probe excitation–contraction coupling in smooth muscle.



