The IL6R variation Asp358Ala is a potential modifier of lung function in subjects with asthma

The Journal of Allergy and Clinical Immunology, 05/04/2012

The IL6R coding single nucleotide polymorphism (SNP) rs2228145 (Asp358Ala) is a potential modifier of lung function in subjects with asthma and might identify subjects at risk for more severe asthma. IL–6 transsignaling might have a pathogenic role in the lung.

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