Correlation of health-related quality of life with other disease severity indices in Indian chronic obstructive pulmonary disease patients Full Text
International Journal of COPD, 05/08/2012
Shavro SA et al. – This study showed that Indian patients with COPD had reduced health–related quality of life (HRQOL). Longer disease duration, patient perception of disease severity, and worsening dyspnea impacted negatively on HRQOL.Methods
- Seventy-three consecutive COPD patients visiting an outpatient pulmonary clinic underwent health-related QOL (HRQOL) assessment using the World Health Organization’s QOL abbreviated questionnaire and St George’s Respiratory Questionnaire (SGRQ).
- Symptom severity and grade of dyspnea were estimated by the Chronic Lung Disease Severity Index (CLD) and Medical Research Council assessments, and patient demographic data were collected.
- Spirometry and 6-minute walk tests were performed to assess lung function and functional status.
- Patients with COPD showed significantly reduced HRQOL when measured by the World Health Organization’s QOL abbreviated questionnaire and the SGRQ.
- CLD estimate for severity of lung disease (P < 0.001), Medical Research Council assessment for dyspnea (P < 0.01), and duration of illness (P < 0.05) showed close correlation with HRQOL.
- Worsening forced expiratory volume in 1 second and 6-minute walk test results closely correlated with poorer HRQOL (P < 0.01).
- No association between QOL and age, quantum of smoking, education, comorbid illnesses, or occupational exposure was found.