Quality of life and metabolic disorders in patients with obstructive sleep apnea
Clinical and Investigative Medicine,  Clinical Article

Bulcun E et al. – The impact of obstructive sleep apnea (OSA) on quality of life can be attributed to excessive daytime sleepiness. Obesity and metabolic disorders in patients with OSA may also negatively affect the quality of life.

Methods
  • Complete assessments were obtained on 111 subjects who diagnosed OSA and 18 nonapneic snoring subjects.
  • Fasting blood samples of all of subjects were taken to determine insulin resistance (IR) and oral glucose tolerance tests were performed to diagnose disorders of glucose metabolism (DGM).
  • Quality of life, with short form (SF)–36, and excessive daytime sleepiness, with epwort sleepness scale (ESS), were evaluated.

Results
  • The mean age of the patients with OSA was higher than that of the nonapneic snoring subjects (48.4 ± 9.6 years and 43.0 ± 11.8 years, respectively; p=0.03).
  • BMI was also significantly higher in the patients with OSA than in the nonapneic snorers (31.0 ± 4.5 and 27.1 ± 4.0, respectively; p=0.001).
  • The mental health component in the patients with OSA was slightly but not significantly lower than the nonapneic snoring subjects (p=0.05).
  • A negative correlation among most domains of quality of life with scores of ESS, body mass index (BMI), presence of hypertension (HT) and DGM was found.
  • Only physicial functioning was negatively correlated with apnea hypopnea index (AHI).
  • In linear regression analysis, there were negative associations among physical functioning with BMI, presence of HT and DGM while there was no association between physicial functioning and AHI.
  • In addition, there were negative correlations between mental health component with BMI and presence of HT in the multivariate analysis.
  • Obese patients with OSA had lower physicial and mental components compared with nonobese patients with OSA.

Please login or register to follow this author.
Are you sure you want to Unfollow this Author?
► Click here to access PubMed, Publisher and related articles...
<< Previous Article | Next Article >>

Your Unread Messages in Pulmonology

See All >> Messages include industry-sponsored communications and special communications from MDLinx

Most Popular Pulmonology Articles

1 Tadalafil in patients with chronic obstructive pulmonary disease: a randomised, double-blind, parallel-group, placebo-controlled trial The Lancet Respiratory Medicine, March 6, 2014    Clinical Article

2 Serial chitotriosidase measurements in sarcoidosis - Two to five year follow-up study Respiratory Medicine, May 30, 2014    Clinical Article

3 Azithromycin maintenance treatment in patients with frequent exacerbations of chronic obstructive pulmonary disease (COLUMBUS): A randomised, double-blind, placebo-controlled trial The Lancet Respiratory Medicine, May 15, 2014    Clinical Article

4 Multicentric study on the beta-blocker use and relation with exacerbations in COPD Respiratory Medicine, June 19, 2014    Clinical Article

5 Twice daily N-acetylcysteine 600mg for exacerbations of chronic obstructive pulmonary disease (PANTHEON): A randomised, double-blind placebo-controlled trial The Lancet Respiratory Medicine, January 30, 2014    Clinical Article

6 Efficacy and safety of once-daily fluticasone furoate/vilanterol (100/25 mcg) versus twice-daily fluticasone propionate/salmeterol (250/50 mcg) in COPD patients Respiratory Medicine, June 23, 2014    Clinical Article

7 Association of azithromycin with mortality and cardiovascular events among older patients hospitalized with pneumonia JAMA, June 4, 2014    Evidence Based Medicine    Clinical Article

8 Benefits of adding fluticasone propionate/salmeterol to tiotropium in COPD: A meta-analysis European Journal of Internal Medicine , June 17, 2014    Evidence Based Medicine    Review Article

9 Double-blind controlled trial of lecithinized superoxide dismutase in patients with idiopathic interstitial pneumonia - short term evaluation of safety and tolerability Full Text BMC Pulmonary Medicine, May 23, 2014    Free full text    Clinical Article

10 Regadenoson use in patients with chronic obstructive pulmonary disease: The state of current knowledge Full Text International Journal of COPD, January 23, 2014    Free full text    Review Article    Clinical Article

11 Inhaled beta-2-agonists/muscarinic antagonists and acute myocardial infarction in COPD patients Respiratory Medicine, June 11, 2014    Clinical Article

12 The efficacy and safety of prone positional ventilation in acute respiratory distress syndrome: Updated study-level meta-analysis of 11 randomized controlled trials Critical Care Medicine, April 18, 2014    Clinical Article

13 Tiotropium in asthma: A systematic review Full Text Journal of Asthma and Allergy, March 11, 2014    Free full text    Evidence Based Medicine    Review Article

14 Glucocorticoid-resistant asthma Journal of Asthma, December 4, 2013    Clinical Article

15 Pneumonitis and pulmonary fibrosis associated with breast cancer treatments Breast Cancer Research and Treatment, June 27, 2014    Review Article

16 Predicting survival after extracorporeal membrane oxygenation for severe acute respiratory failure: The Respiratory Extracorporeal Membrane Oxygenation Survival Prediction (RESP) Score American Journal of Respiratory and Critical Care Medicine, June 18, 2014    Clinical Article

17 The potential role of direct and indirect bronchial challenge testing to identify overtreatment of community managed asthma Clinical & Experimental Allergy, June 19, 2014    Clinical Article

18 Chronic Cough: An Update Mayo Clinic Proceedings, October 3, 2013    Review Article    Clinical Article

19 Initial use of one or two antibiotics for critically ill patients with community-acquired pneumonia: Impact on survival and bacterial resistance Critical Care, November 8, 2013    Clinical Article

20 A randomised phase II study of pemetrexed versus pemetrexed+erlotinib as second-line treatment for locally advanced or metastatic non-squamous non-small cell lung cancer European Journal of Cancer, May 22, 2014    Clinical Article

Indexed Journals in Pulmonology: Chest, Thorax, American Journal of Respiratory and Critical Care Medicinemore

Register now to view all the MDLinx contents (FREE)!

  • Stay current on the latest literature, research and clinical news
  • Get special communications and offers from MDLinx and our sponsors
  • Receive invitations to paid market research
View Samples and Register

Connect with us, stay current.

Receive the latest mecial news
updates for free via email

Sign up!

Subscribe to our free RSS feeds:

Get the latest news in your specialty automatically added to your newsreader or your personal My Yahoo!, Google, My MSN or My AOL page. Learn More

Close