Pain impacts on quality of life and interferes with treatment in adults with cystic fibrosis
Physiotherapy Research International, 05/07/2012Kelemen L et al.
Pain is common in adults with cystic fibrosis (CF), irrespective of clinical status, and may interfere with important physiotherapy treatments. Although pain intensity is generally mild, those with a negative emotional response to pain have significantly impaired health–related quality of life (HRQOL).
This study was an observational study of adults with CF.
Participants completed three questionnaires, the Brief Pain Inventory, Pain Catastrophizing Scale and the CF–Quality of Life questionnaire, when clinically stable and during an acute exacerbation.
A total of 73 participants were included during a period of clinical stability, with 33 repeating the measurements during an acute illness, with a mean (SD) age of 29 (9) years and forced expiratory volume (FEV1) of 60.5 (24.9)% predicted.
Mild pain was reported by 89% of stable participants and 79% of those with exacerbations. Severity of lung disease did not affect prevalence or intensity of pain.
Pain interfered with airway clearance therapy during exacerbations (p<0.012) and exercise regimens when participants were clinically stable (p<0.002) and was related to a poorer physical function, regardless of clinical status (p<0.05).
Although pain intensity was associated with reduced HRQOL (p<0.001), only FEV1 and the degree of pain catastrophizing were independent predictors of poorer HRQOL.
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