IL-4 receptor polymorphisms predict reduction in asthma exacerbations during response to an anti-IL-4 receptor α antagonist

The Journal of Allergy and Clinical Immunology, 05/01/2012

This study demonstrates a significant pharmacogenetic interaction between anti–IL–4 receptor α therapy and IL4RA gene variation, identifying an asthma subgroup that is more responsive to therapy with this antagonist.

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