Roflumilast: a guide to its use in chronic obstructive pulmonary disease

Drugs & Therapy Perspectives, 08/08/2011

Roflumilast is the first selective phosphodiesterase 4 inhibitor indicated to treat severe chronic obstructive pulmonary disease associated with chronic bronchitis in patients with a history of frequent exacerbations. It significantly improves lung function and exacerbation rates, and has an acceptable tolerability profile in this patient population.

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