Your Messages Inbox
Most Viewed Abstracts
1. Report Shows Shift in Starting Salaries for Physicians 2. 2008 Exclusive Survey—Earnings: Good news for primary care income 3. Medicare pay-for-reporting effort draws fire from frustrated doctors 4. Debunking Myths in the US Healthcare System 5. Omega-3 fatty acids for bipolar disorder
Your Article Summary
See Latest ArticlesCo-analgesics - today and tomorrow - A receptor-based overview of therapeutical options
Anästhesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS, 11/17/09
Worner J et al. – The authors describe the peripheral action sites of co–analgesics, such as cannabinoids, capsaicin, bisphosphonates, steroids and somatostatin. The authors also summarise the effect of peripherally and centrally acting ion–channel blockers, e.g. local anaesthetics, carbamazepine and tolperisone working on sodium channels and gabapentine and pregabaline working on calcium channels. Finally, central analgesic mechanisms are discussed, for instance the inhibition of NMDA–receptors by ketamine or magnesium, the stimulation of alpha2–receptors by clonidine, tizanidine or antidepressants, the activation of GABA–receptors through baclofen and other analgesic mechanisms of i.e. ondansetrone and neostigmine.
Related Articles
Factors associated with a continuous regular analgesic use - a population-based study of more than 45 000 Danish women and men 18-45 years of age
Pharmacoepidemiology and Drug Safety, 10/01/09
Relevance Score: 94%
Use of analgesic and sedative drugs in the NICU: integrating clinical trials and laboratory data
Pediatric Research, 11/09/09
Relevance Score: 90%
Clinical pharmacology of analgesics in old age and frailty
Reviews in Clinical Gerontology, 11/10/09
Relevance Score: 89%
The antinociceptive activity of Polygonatum verticillatum rhizomes in pain models
Journal of Ethnopharmacology, 10/28/09
Relevance Score: 88%
Diffuse analgesic effects of unilateral repetitive transcranial magnetic stimulation (rTMS) in healthy volunteers
Pain, 10/13/09
Relevance Score: 88%
Today in Clinical Pharmacology...keeping you current
Receive free subspecialty "5-minute updates" via email
Improvement of Postprandial Endothelial Function after a Single Dose of Exenatide in Individuals with Impaired Glucose Tolerance and Recent Onset Type 2 Diabetes Mellitus
Diabetes Care, 03/22/10
Cardio-selective and non-selective beta-blockers in chronic obstructive pulmonary disease: effects on bronchodilator response and exercise
Internal Medicine Journal, 03/22/10
Oxycodone/acetaminophen at low dosage: An alternative pain treatment for patients with rheumatoid arthritis
Journal of Opioid Management, 03/22/10
Today in Pain Management...keeping you current
Receive free subspecialty "5-minute updates" via email
Pilot study of high-sensitivity troponin T testing to facilitate safe early disposition decisions in patients presenting to the emergency department with chest pain
Internal Medicine Journal, 03/22/10
Oxycodone/acetaminophen at low dosage: An alternative pain treatment for patients with rheumatoid arthritis
Journal of Opioid Management, 03/22/10
Does land-based exercise reduce pain and disability associated with hip osteoarthritis? A meta-analysis of randomized controlled trials
Osteoarthritis and Cartilage , 03/22/10
Today in Clinical Pharmacology...keeping you current
Receive free subspecialty "5-minute updates" via email
Improvement of Postprandial Endothelial Function after a Single Dose of Exenatide in Individuals with Impaired Glucose Tolerance and Recent Onset Type 2 Diabetes Mellitus
Diabetes Care, 03/22/10
Oxycodone/acetaminophen at low dosage: An alternative pain treatment for patients with rheumatoid arthritis
Journal of Opioid Management, 03/22/10
Today in Pain Management...keeping you current
Receive free subspecialty "5-minute updates" via email
Oxycodone/acetaminophen at low dosage: An alternative pain treatment for patients with rheumatoid arthritis
Journal of Opioid Management, 03/22/10
Pharmacokinetics of intranasal fentanyl spray in patients with cancer and breakthrough pain
Journal of Opioid Management, 03/22/10
Pilot study of high-sensitivity troponin T testing to facilitate safe early disposition decisions in patients presenting to the emergency department with chest pain
Internal Medicine Journal, 03/22/10
Today in Clinical Pharmacology...keeping you current
Receive free subspecialty "5-minute updates" via email
Improvement of Postprandial Endothelial Function after a Single Dose of Exenatide in Individuals with Impaired Glucose Tolerance and Recent Onset Type 2 Diabetes Mellitus
Diabetes Care, 03/22/10
Treatment of Cluster Headache in Pregnancy and Lactation
Current Pain and Headache Reports, 03/22/10
Ranolazine-related dyspnea on exertion
The American Journal of Geriatric Pharmacotherapy, 03/22/10
Today in Clinical Pharmacology...keeping you current
Receive free subspecialty "5-minute updates" via email
Improvement of Postprandial Endothelial Function after a Single Dose of Exenatide in Individuals with Impaired Glucose Tolerance and Recent Onset Type 2 Diabetes Mellitus
Diabetes Care, 03/22/10
Treatment of Cluster Headache in Pregnancy and Lactation
Current Pain and Headache Reports, 03/22/10
Weight Gain and Insulin Resistance in Children Treated With Valproate: The Influence of Time
Journal of Child Neurology, 03/22/10
Today in Clinical Pharmacology...keeping you current
Receive free subspecialty "5-minute updates" via email
Improvement of Postprandial Endothelial Function after a Single Dose of Exenatide in Individuals with Impaired Glucose Tolerance and Recent Onset Type 2 Diabetes Mellitus
Diabetes Care, 03/22/10
Cardio-selective and non-selective beta-blockers in chronic obstructive pulmonary disease: effects on bronchodilator response and exercise
Internal Medicine Journal, 03/22/10
Oxycodone/acetaminophen at low dosage: An alternative pain treatment for patients with rheumatoid arthritis
Journal of Opioid Management, 03/22/10
Today in Anesthesiology...keeping you current
Receive free subspecialty "5-minute updates" via email
Opioids and Cannabinoids Interactions: Involvement in Pain Management
Current Drug Targets, 03/22/10
Pharmacokinetics of intranasal fentanyl spray in patients with cancer and breakthrough pain
Journal of Opioid Management, 03/22/10
The effect of intravenous opioid patient-controlled analgesia with and without background infusion on respiratory depression: A meta-analysis
Journal of Opioid Management, 03/22/10
Today in Family Medicine...keeping you current
Receive free subspecialty "5-minute updates" via email
Opioid Analgesics for Persistent Pain in the Older Patient: Part I
Clinical Geriatrics, 03/22/10
Opioids and Cannabinoids Interactions: Involvement in Pain Management
Current Drug Targets, 03/22/10
Pharmacokinetics of intranasal fentanyl spray in patients with cancer and breakthrough pain
Journal of Opioid Management, 03/22/10
Today in Internal Medicine...keeping you current
Receive free subspecialty "5-minute updates" via email
Opioid Analgesics for Persistent Pain in the Older Patient: Part I
Clinical Geriatrics, 03/22/10
Opioids and Cannabinoids Interactions: Involvement in Pain Management
Current Drug Targets, 03/22/10
Pharmacokinetics of intranasal fentanyl spray in patients with cancer and breakthrough pain
Journal of Opioid Management, 03/22/10
Today in Pharmacy...keeping you current
Receive free subspecialty "5-minute updates" via email
Opioid Analgesics for Persistent Pain in the Older Patient: Part I
Clinical Geriatrics, 03/22/10
Opioids and Cannabinoids Interactions: Involvement in Pain Management
Current Drug Targets, 03/22/10
Pharmacokinetics of intranasal fentanyl spray in patients with cancer and breakthrough pain
Journal of Opioid Management, 03/22/10
Today in Pain Management...keeping you current
Receive free subspecialty "5-minute updates" via email
Pharmacokinetics of intranasal fentanyl spray in patients with cancer and breakthrough pain
Journal of Opioid Management, 03/22/10
The effect of intravenous opioid patient-controlled analgesia with and without background infusion on respiratory depression: A meta-analysis
Journal of Opioid Management, 03/22/10
Cellular Mechanisms Underlying the Interaction between Cannabinoid and Opioid System
Current Drug Targets, 03/22/10
Today in Pain Management...keeping you current
Receive free subspecialty "5-minute updates" via email
Treatment of Cluster Headache in Pregnancy and Lactation
Current Pain and Headache Reports, 03/22/10
Oxycodone/acetaminophen at low dosage: An alternative pain treatment for patients with rheumatoid arthritis
Journal of Opioid Management, 03/22/10
Opioids and Cannabinoids Interactions: Involvement in Pain Management
Current Drug Targets, 03/22/10
Article Search
Sponsor
Sponsor