Your Messages Inbox
Most Viewed Abstracts
1. Report Shows Shift in Starting Salaries for Physicians 2. 2008 Exclusive Survey—Earnings: Good news for primary care income 3. Medicare pay-for-reporting effort draws fire from frustrated doctors 4. Debunking Myths in the US Healthcare System 5. Omega-3 fatty acids for bipolar disorder
Your Article Summary
See Latest ArticlesMemantine: a review of studies into its safety and efficacy in treating Alzheimer’s disease and other dementias
Clinical Interventions in Aging, 09/29/09
Thomas SJ et al. – Memantine is an uncompetitive N–methyl–D–aspartate receptor antagonist with moderate affinity. Its mechanism of action is neuroprotective and potentially therapeutic in several neuropsychiatric diseases. It has been approved by the FDA for the treatment of moderate to severe Alzheimer’s disease (AD) either as a monotherapy or in combination with cholinesterase inhibitors. This review covers key studies of memantine’s safety and efficacy in treating moderate to severe AD. It also covers current research into other dementias including but not exclusively mild AD and vascular dementia. Other studies on the efficacy of memantine for other neuropsychiatric diseases are discussed. Memantine is a safe and effective drug that merits further research on several topics. Clinicians should be aware of new studies and potential uses of memantine because of its safety and efficacy.
Related Articles
Benefit Of Memantine In The Treatment Of Alzheimers Disease Not Proven
ScienceDaily, 10/29/09
Relevance Score: 66%
Memantine versus donepezil in mild to moderate Alzheimer's disease: a randomized trial with magnetic resonance spectroscopy
European Journal of Neurology, 11/03/09
Relevance Score: 65%
Critical appraisal of the long-term impact of memantine in treatment of moderate to severe Alzheimer’s disease
Neuropsychiatric Disease and Treatment, 11/04/09
Relevance Score: 64%
Variability in the Prescription of Cholinesterase Inhibitors and Memantine
Dementia and Geriatric Cognitive Disorders, 11/03/09
Relevance Score: 64%
Prevalence of dementia and major dementia subtypes in Spanish populations: A reanalysis of dementia prevalence surveys, 1990-2008
BMC Neurology, 10/23/09
Relevance Score: 47%
Today in Geriatric Psych...keeping you current
Receive free subspecialty "5-minute updates" via email
Attentional Bias for Threat in Older Adults: Moderation of the Positivity Bias by Trait Anxiety and Stimulus Modality
Psychology and Aging, 11/20/09
Replicating the Positivity Effect in Picture Memory in Koreans: Evidence for Cross-Cultural Generalizability
Psychology and Aging, 11/20/09
The assessment of effortful control in childhood: Questionnaires and the Test of Everyday Attention for Children compared
Personality and Individual Differences, 11/19/09
Today in Neuro/Psych Pharmacol...keeping you current
Receive free subspecialty "5-minute updates" via email
Early- and Delayed Antipsychotic Response and Prediction of Outcome in 528 Severely Impaired Patients with Schizophrenia Treated with Amisulpride
Pharmacopsychiatry, 11/20/09
Association of the Glutamate Transporter Gene SLC1A1 With Atypical Antipsychotics-Induced Obsessive-compulsive Symptoms
Archives of General Psychiatry, 11/20/09
QTc interval in a sample of long-term schizophrenia inpatients
Schizophrenia Research, 11/20/09
Today in Neuropsych Sciences...keeping you current
Receive free subspecialty "5-minute updates" via email
Review of Pathological Hallmarks of Schizophrenia: Comparison of Genetic Models With Patients and Nongenetic Models
Schizophrenia Bulletin, 11/20/09
Association of Poor Childhood Fear Conditioning and Adult Crime
American Journal of Psychiatry, 11/20/09
Effects of cognitive pain coping strategies and locus of control on perception of cold pressor pain in healthy individuals: Experimental study
Acute Pain, 11/20/09
Sponsor
Article Search
Sponsor