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See Latest ArticlesMemantine: A Review of its Use in Moderate to Severe Alzheimer's Disease
CNS Drugs, 09/18/09
McKeage K – Memantine is generally well tolerated, with adverse events occurring with a similar incidence to that reported with placebo. In modelled cost–effectiveness analyses, memantine was dominant to no therapy in regard to cost per quality–adjusted life–year (QALY) gained, and the combination of memantine plus donepezil was dominant to donepezil therapy alone in regard to QALYs gained when treatment periods exceeded 1 year in patients with moderate to severe disease. Thus, in the management of patients with moderate to severe Alzheimer's disease, memantine provides an effective treatment option.
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