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See Latest ArticlesGene-environment interactions predict cortisol responses after acute stress: Implications for the etiology of depression
Psychoneuroendocrinology, 09/15/09
Alexander N et al. – This is the first study reporting that 5–HTTLPR and stressful life events interact to predict endocrine stress reactivity in a non–clinical sample. The authors' results underpin the potential moderating role of HPA–axis hyper–reactivity as a premorbid risk factor to increase the vulnerability for depression in subjects with low serotonin transporter efficiency and a history of severe life events.
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