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Reduced neuronal expression of insulin-degrading enzyme in the dorsolateral prefrontal cortex of patients with haloperidol-treated, chronic schizophrenia
Journal of Psychiatric Research, 09/14/09
Bernstein HG et al. – Reduced cortical IDE expression might be part of the disturbed insulin signaling cascades found in schizophrenia. Furthermore, it might contribute to the altered metabolism of certain neuropeptides (IGF–I and IGF–II, beta–endorphin), in schizophrenia.
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