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See Latest ArticlesNicotine Enhances but Does Not Normalize Visual Sustained Attention and the Associated Brain Network in Schizophrenia
Schizophrenia Bulletin, 08/31/09
Hong EL et al. – Activations in brain regions associated with nicotine–induced behavioral improvement were not significantly different between patients and comparison subjects. Thus, nicotine transiently enhanced sustained attention similarly in schizophrenia patients and in healthy comparison smokers. The neural mechanisms for this nicotinic effect in schizophrenia appear similar to those for healthy comparison subjects. However, nicotine, at least in a single sustained dose, does not normalize impaired sustained attention and its associated brain network in schizophrenia.
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