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The effects of the second generation antipsychotics and a typical neuroleptic on collagen-induced platelet aggregation in vitro
World Journal of Biological Psychiatry, 08/26/09
Dietrich–Muszalska A et al. – The obtained results indicate that the difference in action of tested drugs on platelet aggregation may dependent on the various chemical structures of these drugs. Clozapine, risperidone and haloperidol are structurally diverse, and they all significantly reduce platelet aggregability induced by collagen. On the other hand, a close structural analog of clozapine – olanzapine – did not inhibit platelet aggregation.
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