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See Latest ArticlesDoes the presence of a pharmacological substance alter the placebo effect? - results of two experimental studies using the placebo-caffeine paradigm
Human Psychopharmacology: Clinical and Experimental, 08/27/09
Walach H et al. – Effect sizes were medium to large for some outcome parameters in experiment 1 and 2, showing partial replicability of the classical placebo effect. Although not formally significant, differences between the double blind placebo conditions of the two experiments (with and without caffeine present) were medium to small. There was a significant difference between experiment 1 and experiment 2 in the physiological variables, and a near significant interaction effect between groups and experiments in the physiological variables.
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