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See Latest Articlesd-Cycloserine attenuates reactivity to smoking cues in nicotine dependent smokers: A pilot investigation
Drug and Alcohol Dependence, 08/19/09
Santa Ana EJ et al. – These findings provide promising support for DCS combined with cue exposure therapy in attenuating conditioned reactivity to smoking cues.
Methods- Double–blind placebo–controlled pilot laboratory study
- 25 smokers were recruited from the general community and randomized to DCS or placebo, plus cue exposure therapy.
- DCS significantly attenuated smoking cue reactivity in response to in–vivo smoking cues based on physiological reactivity and subjective urge–to–smoke ratings and led to a significantly smaller expired carbon monoxide (CO) level at the one–week follow–up compared to placebo, although exploratory analyses indicated no effect on smoking behavior overall.
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