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Risperidone long acting injection: Findings of a 2-year retrospective follow-up study
International Journal of Psychiatry in Clinical Practice, 08/19/09
Deslandes PN et al. – The proportion of patients remaining on RLAI at 2 years was 33%. Limitations of the naturalistic methodology used in this study hindered any precise determination of which patients were likely to continue RLAI. However, it was apparent that a history of previous treatment failure with at least two antipsychotics was associated with RLAI treatment discontinuation.
Methods- All patients who received RLAI between July 2002 and December 2004 were identified from pharmacy records, and data collected by retrospective case note review.
- Eighty–four patients were included in the study and 56 discontinued at 2 years. The most common reason for treatment discontinuation was lack of effectiveness, accounting for 32 patients, whilst eight patients discontinued due to adverse effects.
- The most common reason for treatment discontinuation was lack of effectiveness, accounting for 32 patients, whilst eight patients discontinued due to adverse effects.
- Patients remaining on treatment spent 67% of the time in an outpatient setting.
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