Your Messages Inbox
Most Viewed Abstracts
1. Report Shows Shift in Starting Salaries for Physicians 2. 2008 Exclusive Survey—Earnings: Good news for primary care income 3. Medicare pay-for-reporting effort draws fire from frustrated doctors 4. Debunking Myths in the US Healthcare System 5. Omega-3 fatty acids for bipolar disorder
Your Article Summary
See Latest ArticlesA Randomized, Double-Blind, Placebo-Controlled Pilot Study of Naltrexone in Outpatients With Bipolar Disorder and Alcohol Dependence
Alcoholism, 08/13/09
Brown ES et al. – Results suggest the potential value and acceptable tolerability of naltrexone for alcohol dependence in bipolar disorder patients. A larger trial is needed to establish efficacy.
Methods- Fifty adult outpatients with bipolar I or II disorders and current alcohol dependence with active alcohol use were randomized to 12 weeks of naltrexone (50 mg/d) add–on therapy or placebo.
- Both groups received manual–driven cognitive behavioral therapy designed for patients with bipolar disorder and substance–use disorders.
- Drinking days and heavy drinking days, alcohol craving, liver enzymes, and manic and depressed mood symptoms were assessed.
- The 2 groups were similar in baseline and demographic characteristics.
- Naltrexone showed trends (p < 0.10) toward a greater decrease in drinking days (binary outcome), alcohol craving, and some liver enzyme levels than placebo.
- Side effects were similar in the 2 groups. Response to naltrexone was significantly related to medication adherence.
Related Articles
Packages of Care for Alcohol Use Disorders in Low- And Middle-Income Countries
PLoS Medicine, 10/28/09
Relevance Score: 81%
Acute alcohol impairs conditioning of a behavioural reward-seeking response and inhibitory control processesimplications for addictive disorders
Addiction, 11/19/09
Relevance Score: 80%
Naltrexone for the treatment of alcohol dependence among African Americans: Results from the COMBINE Study
Drug and Alcohol Dependence, 10/26/09
Relevance Score: 80%
Differences between men and women in the course of opiate dependence: is there a telescoping effect
European Archives of Psychiatry and Clinical Neuroscience, 10/26/09
Relevance Score: 80%
Improving Clinical Outcomes in Treating Heroin Dependence: Randomized, Controlled Trial of Oral or Implant Naltrexone
Archives of General Psychiatry, 10/09/09
Relevance Score: 80%
Today in Mood Disorders...keeping you current
Receive free subspecialty "5-minute updates" via email
Probable levetiracetam-associated depression in the elderly: Two case reports
The American Journal of Geriatric Pharmacotherapy, 12/20/09
Suicide in the Northern Territory, 2001-2006
Australian and New Zealand Journal of Psychiatry, 12/20/09
Is lithium in a class of its own? A brief profile of its clinical use
Australian and New Zealand Journal of Psychiatry, 12/20/09
Today in Neuro/Psych Pharmacol...keeping you current
Receive free subspecialty "5-minute updates" via email
Probable levetiracetam-associated depression in the elderly: Two case reports
The American Journal of Geriatric Pharmacotherapy, 12/20/09
Quetiapine-associated dysphagia
World Journal of Biological Psychiatry, 12/19/09
Zuclopenthixol-induced neuroleptic malignant syndrome presenting as fever of unknown origin, hyperglycaemia and acute myocardial infarction in a 60-year-old man
World Journal of Biological Psychiatry, 12/19/09
Today in Neuro/Psych Pharmacol...keeping you current
Receive free subspecialty "5-minute updates" via email
Probable levetiracetam-associated depression in the elderly: Two case reports
The American Journal of Geriatric Pharmacotherapy, 12/20/09
Quetiapine-associated dysphagia
World Journal of Biological Psychiatry, 12/19/09
Zuclopenthixol-induced neuroleptic malignant syndrome presenting as fever of unknown origin, hyperglycaemia and acute myocardial infarction in a 60-year-old man
World Journal of Biological Psychiatry, 12/19/09
Today in Substance Abuse...keeping you current
Receive free subspecialty "5-minute updates" via email
Repeated intravenous ketamine therapy in a patient with treatment-resistant major depression
World Journal of Biological Psychiatry, 12/20/09
Impact of Substance Use Disorders on Recovery From Episodes of Depression in Bipolar Disorder Patients: Prospective Data From the Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD)
American Journal of Psychiatry, 12/19/09
Characteristics of Opioid-Using Pregnant Women Who Accept or Refuse Participation in a Clinical Trial: Screening Results from the MOTHER Study
American Journal of Drug & Alcohol Abuse, 12/19/09
Sponsor
Article Search
Sponsor
Sponsor