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See Latest ArticlesUnexpected interaction between quetiapine and valproate in patients with bipolar disorder
General Hospital Psychiatry, 08/12/09
Huang CC et al. – The authors report two patients with bipolar disorder who developed delirium when prescribed quetiapine as an adjunct to valproate for acute mania. Both had previously developed mild renal insufficiency after an episode of lithium intoxication. The delirium resolved after quetiapine was discontinued. Unexpected interactions may occur when medications are combined without being subject to controlled clinical trials.
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