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Persistent Genital Arousal Disorder (PGAD): Case Report of Long-Term Symptomatic Management with Electroconvulsive Therapy
The Journal of Sexual Medicine, 08/18/09
Korda JB et al. – Based on the patient's bipolar disorder, the mechanism of action of ECT and the observation of ECT effectiveness on her PGAD, authors hypothesize that bipolar disorder led to central hyperactive dopamine release, an important component in the pathophysiology of her PGAD; central serotonin deficiency after selective serotonin–reuptake inhibitor (SSRI) withdrawal resulted in a lack of inhibition of sexual excitement; ECT resulted in lowering of the hyperstimulated central dopamine release; and ECT led to an increase in sexual inhibition by stimulating serotonin activity.
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Depression and Related Psychological Factors in Heart Disease
Harvard Review of Psychiatry, 12/14/09
Misdiagnosis of bipolar disorder as borderline personality disorder: clinical and economic consequences
World Journal of Biological Psychiatry, 12/14/09
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