Your Messages Inbox
Most Viewed Abstracts
1. Report Shows Shift in Starting Salaries for Physicians 2. 2008 Exclusive Survey—Earnings: Good news for primary care income 3. Medicare pay-for-reporting effort draws fire from frustrated doctors 4. Debunking Myths in the US Healthcare System 5. Omega-3 fatty acids for bipolar disorder
Your Article Summary
See Latest ArticlesEconomic evaluation of cholinesterase inhibitor therapy for dementia: comparison of Alzheimers disease and Dementia with Lewy bodies
International Journal of Geriatric Psychiatry, 08/05/09
Gustavsson A et al. – The cost per QALY gained of cholinesterase treatment of all patients with DLB (including those with MMSE outside the 10–20 range) is comparable to that of patients with moderate AD, and is probably cost saving.
Methods- Used 4–month open label follow–up data from routine memory clinic patients.
- There were 852 patients with AD and 112 with DLB.
- We applied three predictive models to estimate clinical and economic outcomes at five years, comparing AD and DLB patients with hypothetical untreated controls.
- The mean improvement in MMSE in 852 AD patients was 0.57 (SD 3.4) at 4 months, and in the subgroup with baseline MMSE of 10–20 (moderate) was 1.6 (SD 3.7).
- Overall, the 112 DLB patients improved by 1.4 (SD 3.7).
- DLB patients with an MMSE 10–20 improved by 3.1 (SD 4.5) points.
- These efficacy data were input into the SHTAC, microsimulation and Markov models and produced estimated costs per QALY gained (CQG) for all AD of £194,066, £67,904 and £123,935 respectively.
- n comparison, the CQGs for all DLB were £46,794, £2,706 and £35,922. For the moderate subgroups only the SHTAC and microsimulation models were applicable.
- These gave CQG estimates for moderate AD of £39,664 and cost saving respectively.
- For moderate DLB, both estimates were cost saving.
Related Articles
Review: statins do not protect against development of dementia
Evidence-Based Mental Health, 10/30/09
Relevance Score: 64%
High Systolic and Pulse Pressure Levels Are Associated with Better Cognitive Performance in Patients with Probable Alzheimer's Disease: A Cross-Sectional Observational Study in a Geriatric Outpatient Population
Dementia and Geriatric Cognitive Disorders, 10/23/09
Relevance Score: 64%
Does Diabetes Speed Up Memory Loss In Alzheimers Disease?
ScienceDaily, 10/28/09
Relevance Score: 46%
High Blood Pressure Likely in Alzheimers Offspring
MedLinePlus, 11/04/09
Relevance Score: 45%
Inflammation, Genes, and Hypertension All Contribute to Alzheimer's Risk
U.S. News & World Report, 11/03/09
Relevance Score: 45%
Today in Geriatric Psych...keeping you current
Receive free subspecialty "5-minute updates" via email
Low Respiratory Function Increases the Risk of Depressive Symptoms in Later Life in Men
Psychosomatic Medicine, 12/02/09
Who will be eligible? An investigation of the dementia population eligible for cholinesterase treatment following the change in NICE guidance
International Journal of Geriatric Psychiatry, 12/01/09
Medically Unexplained Physical Symptoms in Elderly People: A Pilot Study of Psychiatric Geriatric Characteristics
American Journal of Geriatric Psychiatry, 12/01/09
Today in Neuro/Psych Pharmacol...keeping you current
Receive free subspecialty "5-minute updates" via email
Quetiapine treatment and improved cognitive functioning in borderline personality disorder
Human Psychopharmacology: Clinical and Experimental, 12/04/09
Mania associated with antidepressant treatment: comprehensive meta-analytic review
Acta Psychiatrica Scandinavica, 12/04/09
Lithium but not carbamazepine augments antidepressant efficacy of mirtazapine in unipolar depression: An open-label study
World Journal of Biological Psychiatry, 12/03/09
Today in Neuropsych Sciences...keeping you current
Receive free subspecialty "5-minute updates" via email
Change in delusions is associated with change in jumping to conclusions
Psychiatry Research, 12/04/09
Specific and Generalized Neuropsychological Deficits: A Comparison of Patients With Various First-Episode Psychosis Presentations [research-article]
American Journal of Psychiatry, 12/03/09
Spectroscopic findings in attention-deficit/hyperactivity disorder: Review and meta-analysis
World Journal of Biological Psychiatry, 12/03/09
Sponsor
Article Search
Sponsor