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Fibromyalgia: Diagnosis and treatment options
Gender Medicine, 07/31/09
Marcus DA et al. – Review concludes that fibromyalgia is a common, disabling, chronic pain condition that predominantly affects women. Symptoms can be effectively treated using both drug and nondrug therapies; treatment benefits appear largely independent of patient sex.
Methods- Review article to provide updated information from database literature on:
- Fibromyalgia epidemiology, including gender differences
- Psychological comorbidity, and
- Treatment with medication and nonmedication therapies
- Literature review from Jan 2000 to Oct 2008 using the PubMed and EMBASE databases
- Search terms: fibromyalgia, exercise, gender, nonpharmacologic, placebo-controlled, randomized, and treatment
- New epidemiologic data support important differences in fibromyalgia symptom severity between the sexes and the important role of comorbid psychological distress
- Physicians diagnose fibromyalgia in women at an ~3- to 6-fold rate compared with men
- Clinical trials and treatment guidelines reinforce effective treatment with medication and nonpharmacologic therapy
- Strongest evidence suggests effective treatment of fibromyalgia with duloxetine and milnacipran
- Efficacy with gabapentin, pramipexole, pregabalin, tramadol, and IV tropisetron is also reported
- Nonpharmacologic treatments:
- Fitness and strengthening exercise
- Warm-water therapy, and
- Psychological pain management techniques
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