Your Messages Inbox
Most Viewed Abstracts
1. Report Shows Shift in Starting Salaries for Physicians 2. 2008 Exclusive Survey—Earnings: Good news for primary care income 3. Medicare pay-for-reporting effort draws fire from frustrated doctors 4. Debunking Myths in the US Healthcare System 5. Omega-3 fatty acids for bipolar disorder
Your Article Summary
See Latest ArticlesSerum brain-derived neurotrophic factor and peripheral indicators of the serotonin system in underweight and weight-recovered adolescent girls and women with anorexia nervosa
Journal of Psychiatry & Neuroscience , 07/06/09
Ehrlich S et al. - BDNF levels in patients with anorexia nervosa depend on the state of illness and the degree of hypoleptinemia. Upregulation of BDNF in weight-recovered patients with anorexia nervosa could be part of a regenerative process after biochemical and molecular neuronal injury due to prolonged malnutrition. Associations between the BDNF and the 5-HT system in humans remain to be established.
Methods- Determined serum BDNF, platelet 5-HT content and platelet 5-HT uptake in 33 patients in the acAN group, 20 patients in the recAN group and 33 controls. Plasma leptin served as an indicator of malnutrition.
- Patients in the acAN group were aged 14–29 years and had a mean body mass index (BMI) of 14.9 (standard deviation [SD] 1.4) kg/m2.
- Those in the recAN group were aged 15–29 years and had a mean BMI of 20.5 (SD 1.3) kg/m2 and the controls were aged 15–26 years and had a BMI of 21.4 (SD 2.1) kg/m2.
- The mean serum BDNF levels were significantly increased in the recAN group compared with the acAN group (8820, SD 3074 v. 6161, SD 2885 pg/mL, U = 154.5, p = 0.001).
- There were no significant associations between BDNF and either platelet 5-HT content or platelet 5-HT uptake.
- Among patients with anorexia nervosa, the study found significant positive linear relations between BDNF and BMI (r = 0.312, p = 0.023) and between BDNF and leptin (r = 0.365, p = 0.016).
Related Articles
Brain-derived neurotrophic factor gene polymorphisms and serum levels in Chinese atopic dermatitis patients
Journal of the European Academy of Dermatology and Venereology, 10/26/09
Relevance Score: 80%
Increased levels of interleukin 33 in sera and synovial fluid from patients with active rheumatoid arthritis
Journal of Rheumatology, 11/18/09
Relevance Score: 79%
Novel approaches for mechanistic understanding and predicting preeclampsia
Journal of Reproductive Immunology, 10/19/09
Relevance Score: 79%
Investigation of occurrence of osteonecrosis of the femoral head after increasing corticosteroids in patients with recurring systemic lupus erythematosus
Rheumatology International, 10/12/09
Relevance Score: 79%
Proinflammatory cytokines synergistically enhance the production of chemokine ligand 20 (CCL20) from rheumatoid fibroblast-like synovial cells in vitro and serum CCL20 is reduced in vivo by biologic disease-modifying antirheumatic drugs
Journal of Rheumatology, 10/05/09
Relevance Score: 79%
Today in Child/Adolescent Psych...keeping you current
Receive free subspecialty "5-minute updates" via email
Auditory Hallucinations in Dissociative Identity Disorder and Schizophrenia With and Without a Childhood Trauma History: Similarities and Differences
The Journal of Nervous and Mental Disease, 12/15/09
A medical record review for functional somatic symptoms in children
Journal of Psychosomatic Research, 12/15/09
The Long-Term Effects of Breastfeeding on Child and Adolescent Mental Health: A Pregnancy Cohort Study Followed for 14 Years
The Journal of Pediatrics, 12/15/09
Today in Eating Disorders...keeping you current
Receive free subspecialty "5-minute updates" via email
Incidence of Parkinson's Disease in Bulgaria
Neuroepidemiology , 12/15/09
Recurrent acute hepatic dysfunction in severe anorexia nervosa
International Journal of Eating Disorders, 12/14/09
Digestive complication in severe malnourished anorexia nervosa patient: A case report of necrotizing colitis
International Journal of Eating Disorders, 12/10/09
Today in Neuro/Psych Pharmacol...keeping you current
Receive free subspecialty "5-minute updates" via email
Milnacipran: Beyond a Role of Antidepressant
Clinical Neuropharmacology, 12/15/09
Effects of the GABA-reuptake Inhibitor Tiagabine on Panic and Anxiety in Patients with Panic Disorder
Pharmacopsychiatry, 12/15/09
Catatonia and Its Treatment
Schizophrenia Bulletin, 12/15/09
Today in Neuro/Psych Pharmacol...keeping you current
Receive free subspecialty "5-minute updates" via email
Milnacipran: Beyond a Role of Antidepressant
Clinical Neuropharmacology, 12/15/09
Effects of the GABA-reuptake Inhibitor Tiagabine on Panic and Anxiety in Patients with Panic Disorder
Pharmacopsychiatry, 12/15/09
Catatonia and Its Treatment
Schizophrenia Bulletin, 12/15/09
Today in Other Psychiatry...keeping you current
Receive free subspecialty "5-minute updates" via email
Use of Drugs, Coping Styles, Mental Absorption and Some Outcomes Related to Health and Social Activity
European Addiction Research, 12/15/09
Auditory Hallucinations in Dissociative Identity Disorder and Schizophrenia With and Without a Childhood Trauma History: Similarities and Differences
The Journal of Nervous and Mental Disease, 12/15/09
Gray matter, white matter, brain, and intracranial volumes in first-episode bipolar disorder: a meta-analysis of magnetic resonance imaging studies
Bipolar Disorders, 12/15/09
Sponsor
Article Search
Sponsor
Sponsor