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Comparison of health care use and costs in newly diagnosed and established patients with fibromyalgia
The Journal of Pain, 06/30/09

White LA et al. – Study reports that established fibromyalgia patients use more medical resources and have higher rates of concomitant medication use than newly diagnosed fibromyalgia patients. Findings can help educate providers regarding optimal drug treatment patterns in this population.

• Claims database analysis to describe prescription and medical use in pts with newly diagnosed and established fibromyalgia
• Privately insured pts with 2+ myalgia/myositis claims (1999-2005) were categorized as newly diagnosed or established
• This dichotomy involves comparisons between prediagnosis (S1) and postdiagnosis (S2) stages in the newly diagnosed and between newly diagnosed (S2) and established patients (S3)

• Use of APS guideline medications increased across stages:
  • Selective serotonin reuptake inhibitors (SSRIs) (S1, S2, S3: 20.6%, 22.9%, 25.3%)
  • Serotonin norepinephrine reuptake inhibitors (SNRIs) (4.5%, 6.4%, 8.9%)
  • Pregabalin/gabapentin (5.4%, 7.4%, 8.8%)
  • Benzodiazepines (19.0%, 21.1%, 24.2%)
  • Non-benzodiazepine sedatives (9.1%, 11.5%, 13.7%), and
  • Opioids (39.5%, 43.3%, 43.9%)
• Use of multiple therapeutic classes also increased across stages: 3+ classes (7.1%, 9.6%, 11.8%)
• Office visits to providers increased, on average, after diagnosis:
  • Primary care (70.9%, 78.3%, 76.3%)
  • Chiropractors (28.8%, 51.1%, 53.3%)
  • Rheumatologists (4.2%, 9.9%, 10.5%)
  • Mental health (6.4%, 7.3%, 8.3%)
• Average health care costs rose after diagnosis in the newly diagnosed group

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Olanzapine for the Treatment of Acquired Neurogenic Stuttering
Journal of Psychiatric Practice, 12/01/09

The effect of atypical antipsychotics on pituitary gland volume in patients with first-episode psychosis: A longitudinal MRI study
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Risperidone long acting injection: Findings of a 2-year retrospective follow-up study
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Autistic disorder symptoms in Rett syndrome
Autism, 12/01/09

Seasonal trends in depressive problems among United States children and adolescents: A representative population survey
Psychiatry Research, 12/01/09

Olanzapine for the Treatment of Acquired Neurogenic Stuttering
Journal of Psychiatric Practice, 12/01/09

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