Psychiatry Medical News about Duloxetine

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Duloxetine in obese binge eater outpatients: preliminary results from a 12-week open trial
Human Psychopharmacology: Clinical and Experimental, 06/26/09

Leombruni P et al. - Although preliminary, results from this open trial suggest that duloxetine may be a successful option to reduce binge eating and depressive symptoms in both obese BED and s-BED outpatients.

Methods

Forty-five patients with BED or binge eating with sub-threshold symptoms (s-BED) with high eating impulsivity, received duloxetine 60-120 mg/day for 12 weeks.

Results

A significant reduction in number of binges/week was observed in BED patients; statistical analyses performed on the whole sample revealed significant reductions in scores on the binge eating scale (BES) and the Beck depression inventory (BDI), weight, body mass index (BMI), clinical global impression, and the bulimia scale of the eating disorder inventory-2.

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Duloxetine for treating painful neuropathy or chronic pain
Cochrane Reviews, 10/08/09 Relevance Score: 88%

The short- and long-term effect of duloxetine on painful physical symptoms in patients with generalized anxiety disorder: Results from three clinical trials
Journal of Anxiety Disorders, 11/13/09 Relevance Score: 87%

Use of Duloxetine in Pregnancy and Lactation
Annals of Pharmacotherapy, 10/13/09 Relevance Score: 83%

What Makes Patients with Fibromyalgia Feel Better? Correlations Between Patient Global Impression of Improvement and Changes in Clinical Symptoms and Function: A Pooled Analysis of 4 Randomized Placebo-controlled Trials of Duloxetine
Journal of Rheumatology, 10/16/09 Relevance Score: 82%

Use of Antidepressants for Management of Hot Flashes
Pharmacotherapy, 10/27/09 Relevance Score: 80%