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Use of aripiprazole in tardive dyskinesia: An open label study of six cases
World Journal of Biological Psychiatry, 06/10/09
Rajarethinam R et al. - The study supports our hypothesis that clinically stable patients with moderate tardive dyskinesia who are under treatment with other first- or second-generation antipsychotics may benefit from switching to aripiprazole with a reduction of TD symptoms but with out any significant benefit in psychiatric symptoms.
Methods- Six clinically stable patients with schizophrenia or Schizoaffective disorder and a moderate to severe TD participated in this study.
- They were systematically cross-titrated from their current medication to aripiprazole and maintained for 16 weeks.
- The mean extra pyramidal symptom score measured by Abnormal Involuntary Movement Scale (AIMS) improved from a baseline score of 15.8 to final score of 5 (paired t-test; P=0.0009).
- The severity of psychiatric symptoms remained unchanged
Today in Anxiety...keeping you current
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An algorithm for the pharmacological treatment of depression
Acta Psychiatrica Scandinavica, 11/04/09
Impulsivity, personality and bipolar disorder
European Psychiatry , 11/06/09
Estimation of clonazepam abuse liability: a new method using a reimbursed drug database
International Clinical Psychopharmacology, 10/20/09
Today in Neuropsych Sciences...keeping you current
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Impulsivity, personality and bipolar disorder
European Psychiatry , 11/06/09
The role of dopamine in bipolar disorder
Bipolar Disorders, 11/18/09
Serum brain-derived neurotrophic factor in bipolar and unipolar depression: A potential adjunctive tool for differential diagnosis
Journal of Psychiatric Research, 11/20/09
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Is Monotherapy as Good as Polypharmacy in Long-Term Treatment of Bipolar Disorder
Canadian Journal of Psychiatry, 11/16/09
Cardiometabolic Risk of Second-Generation Antipsychotic Medications During First-Time Use in Children and Adolescents
JAMA, 10/28/09
Asenapine versus olanzapine in acute mania: a double-blind extension study
Bipolar Disorders, 10/22/09
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Cardiometabolic Risk of Second-Generation Antipsychotic Medications During First-Time Use in Children and Adolescents
JAMA, 10/28/09
Impact of real-world ziprasidone dosing on treatment discontinuation rates in patients with schizophrenia or bipolar disorder
Schizophrenia Research, 11/18/09
Changes in metabolic syndrome parameters in patients with schizoaffective disorder who participated in a randomized, placebo-controlled trial of topiramate
Asian Journal of Psychiatry, 11/09/09
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