Safety and Efficacy of Quetiapine in Bipolar Depression
Annals of Pharmacotherapy, 10/13/2009
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Bogart GT et al. – Based on the literature reviewed here, quetiapine appears to be a safe and efficacious short–term treatment option for bipolar depression. Patients with bipolar type I showed greater improvement on the MADRS than those with bipolar type II ... Patients with a rapid–cycling disease course showed an improvement in depressive symptoms, regardless of bipolar type.
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Subgenual cingulate volumes in offspring of bipolar parents and in sporadic bipolar patients
European Archives of Psychiatry and Clinical Neuroscience, 10/13/2009
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Hajek T et al. – SGC volume abnormalities were absent in unaffected, affected relatives of bipolar patients as well as sporadic bipolar patients and thus did not meet criteria for endophenotype ... bipolar disorder
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Bipolar Disorder Patient Care Opportunities: Let's Answer the Call
Annals of Pharmacotherapy, 10/16/2009
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Caley CF – Bipolar disorder is a brain illness with complexities in its composition and treatment. Results from the National Comorbidity Survey Replication study estimate the lifetime prevalence of bipolar spectrum illnesses ... treated suboptimally and to be at risk of suffering extensive disability. Pharmacists are in a key position to deliver important pharmacy care services to patients who have bipolar disorder and receive treatments in need of close monitoring.
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Stability of symptoms across major depressive episodes in bipolar disorder
Bipolar Disorders, 11/20/2009
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Perlis RH et al. – While the overall dimensional structure of depressive symptoms lacks temporal stability, individual symptoms including suicidality, mood, psychomotor, and neurovegetative symptoms are stable across major depressive episodes in bipolar disorder and ... be considered in future investigations of course and pathophysiology in bipolar disorder.
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The role of dopamine in bipolar disorder
Bipolar Disorders, 11/19/2009
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Cousins DA et al. – Multiple lines of evidence, including data from pharmacological interventions and structural and functional magnetic resonance imaging studies, suggest that the dopaminergic system may play a central role in bipolar disorder.
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Predominant polarity and temperament in bipolar and unipolar affective disorders
Journal of Affective Disorders, 11/12/2009
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Mazzarini L et al. – The authors' results show that both bipolar I MP and DP subgroups are temperamentally similar and different from UP. Depression in DP bipolar I patients should be viewed as the overlap of ... temperament. These findings confirm the value of the predominant polarity concept as well as the importance of temperaments to separate bipolar from unipolar disorders.
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Epidemiology and Management of Anxiety in Patients with Bipolar Disorder
CNS Drugs, 10/30/2009
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Kauer–Sant'AM et al. – The co–occurrence of anxiety and bipolar disorder has implications for diagnosis, clinical outcome, treatment and prognosis. Careful screening for co–morbid anxiety symptoms and ... patients with bipolar disorder.
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Anxiety and Outcome in Bipolar Disorder
American Journal of Psychiatry, 10/08/2009
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Coryell W et al. – The presence of higher levels of anxiety during bipolar mood episodes appears to mark an illness of substantially greater long–term depressive morbidity.
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Treatment of Bipolar Disorders and Metabolic Syndrome: Implications for Primary Care
Postgraduate Medicine, 10/15/2009
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Bell PF et al. – Recognition of the prevalence of mood disorders and increased availability of medication options have led to calls for treating bipolar disorders in the primary care setting. Second&ndash ... treating bipolar disorders because of their efficacy and perceived safety relative to first–generation antipsychotic medications. Metabolic syndrome is a constellation of risk factors for cardiovascular disease and type 2 diabetes mellitus, which may emerge when treating bipolar disorders with ... the authors offer guidelines for monitoring patient status regarding metabolic syndrome and for providing interventions to promote healthy diet and exercise.
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Understanding Bipolar Disorder; it's symptoms, effects and treatments
Internet Source, 11/05/2009
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Although bipolar disorder is classified as a mood disorder, nearly all people with bipolar disorder also experience a wide variety of non–mood symptoms, like anxiety, substance misuse attention problems and even medical ... asthma and obesity.
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