Asenapine effective in treating agitation
As reported in Acta Psychiatrica Scandinavica, treatment of agitation with sublingual asenapine (10 mg) was shown to be effective. Improvement in the PANSS-EC was comparable to the effect of intramuscular anti-psychotics.
Risk factors for suicidal ideations in bipolar disorder
As reported in Bipolar Disorders, the following risk factors were associated with suicidal ideations in patients with bipolar disorder (n=130): grade of severity of current episode (OR=22.601); family history of suicide attempt (OR=18.06); preceding life event (OR=3.797); and past history of suicidal event (OR=3.11).
Obesity and hypertension associated with impaired cognition in BPD
As reported in Bipolar Diseases, obesity and treated hypertension are associated with decreased global cognitive ability in patients with bipolar disease (n=341), but not schizophrenia (n=417).