MDLinx Psychiatry is your one-stop shop for the peer-reviewed journal articles published in your field. We sort, rank and summarize the literature within 24 hours – hot off the presses! – so you can stay current without drowning in those piles of Current Psychiatry, Bipolar Disorders, and American Journal of Psychiatry. Also find bonus content like clinical pearls from The Smartest Psychiatrist Physician Review and daily quiz competition. Not sure where to start? Skim some of the recent “must read” articles highlighted by our own physician editor D. Scott Cunningham, MD, PhD.
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761 A Pilot Study of Lis-Dexamfetamine Dimesylate (LDX/SPD489) to Facilitate Smoking Cessation in Nicotine-Dependent Adults With ADHD Journal of Attention Disorders, April 19, 2012 Clinical Article
762 Plasma clozapine and norclozapine in relation to prescribed dose and other factors in patients aged 65years and over: data from a therapeutic drug monitoring service, 1996-2010 Human Psychopharmacology: Clinical and Experimental, April 19, 2012
763 Pregnancies exposed to methadone, methadone and other illicit substances, and poly-drugs without methadone: A comparison of fetal neurobehaviors and infant outcomes Drug and Alcohol Dependence, April 19, 2012
764 Optimizing clozapine through clinical decision making Acta Psychiatrica Scandinavica, April 18, 2012 Clinical Article
765 Effectiveness of two formulations of oral olanzapine in patients with schizophrenia or bipolar disorder in a natural setting: results from a 1-year European observational study Human Psychopharmacology: Clinical and Experimental, April 18, 2012 Clinical Article
766 Outcomes on the pharmacopsychometric triangle in bupropion-SR vs. buspirone augmentation of citalopram in the STAR*D trial Acta Psychiatrica Scandinavica, April 18, 2012 Clinical Article
767 Randomized clinical trials underestimate the efficacy of antidepressants in less severe depression Acta Psychiatrica Scandinavica, April 18, 2012 Clinical Article
768 Post-Treatment Outcomes in a Double-Blind, Randomized Trial of Sertraline for Alcohol Dependence Alcoholism: Clinical and Experimental Research, April 17, 2012 Clinical Article
769 Childhood maltreatment and social anxiety disorder: implications for symptom severity and response to pharmacotherapy Depression and Anxiety, April 17, 2012 Clinical Article
770 A Randomized Placebo-Controlled Trial of d-Cycloserine to Enhance Exposure Therapy for Posttraumatic Stress Disorder Biological Psychiatry, April 16, 2012 Clinical Article
771 Evidence for Chronically Altered Serotonin Function in the Cerebral Cortex of Female 3,4-Methylenedioxymethamphetamine Polydrug Users Full Text JAMA Psychiatry, April 16, 2012 Clinical Article
772 A randomized clinical study of Lu AA21004 in the prevention of relapse in patients with major depressive disorder Journal of Psychopharmacology, April 13, 2012 Clinical Article
773 Effect of concurrent substance use disorder on the effectiveness of single and combination antidepressant medications for the treatment of major depression: an exploratory analysis of a single-blind randomized trial Depression and Anxiety, April 13, 2012 Clinical Article
774 A randomized controlled trial of allopurinol vs. placebo added on to antipsychotics in patients with schizophrenia or schizoaffective disorder Schizophrenia Research, April 12, 2012 Clinical Article
775 Prenatal Antipsychotic Exposure and Neuromotor Performance During Infancy JAMA Psychiatry, April 11, 2012 Clinical Article
776 Randomized trial of standard methadone treatment compared to initiating methadone without counseling: 12-month findings Addiction, April 10, 2012 Clinical Article
777 Effects of drop-out on efficacy estimates in five Cochrane reviews of popular antipsychotics for schizophrenia Acta Psychiatrica Scandinavica, April 10, 2012 Clinical Article
778 A Randomized Controlled Trial of CBT Therapy for Adults with ADHD with and without Medication Full Text BMC Psychiatry, April 10, 2012 Clinical Article
779 Retinoic acid as target for local pharmacokinetic interaction with modafinil in neural cells European Archives of Psychiatry and Clinical Neuroscience, April 10, 2012 Clinical Article
780 Individual psychomotor impairment in relation to zopiclone and ethanol concentrations in blood a randomized controlled double-blinded trial Addiction, April 10, 2012
As published in the American Journal of Obstetrics and Gynecology, risk factors for postpartum depression among abused women included age 15-19 (aOR=2.29) and > 35 years of age (aOR=2.33). In non-abused women, risk factors for postpartum depression include unemployment (aOR=1.41), foreign birth (aOR=2.04), and low income (aOR=1.68). Postpartum depression was also associated with women abused prior to pregnancy (aOR=3.28), abuse beginning postpartum (aOR=4.76), and abuse resuming postpartum (aOR=3.81).
Read the article summaryAs published in the British Journal of Psychiatry, low cardiovascular fitness at 18 years of age (n = 1,117,292; follow-up, 3-40 y) is associated with an increased risk of severe depression (HR = 1.96).
Read the article summaryAs published in Clinical Drug Investigation, an initial amisulpride dose of 800 mg (n=38) is more effective that 400 mg with dose titration (n=30) in patients with an acute exacerbation of schizophrenia. A greater number of patients in the 800 mg group than the 400 mg with dose titration group had a 30% reduction in the Positive and Negative Symptom Scale after 4 (68.4% vs. 40.0%) and 6 weeks (71.1% vs. 43.3%).
Read the article summary1 Nidotherapy for people with schizophrenia Cochrane Reviews, April 11, 2013 Evidence Based Medicine
2 Augmentation with Atypical Antipsychotics for Depression: A Review of Evidence-Based Support from the Medical Literature Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, March 13, 2013 Evidence Based Medicine
3 Long-term safety and tolerability of aripiprazole once-monthly in maintenance treatment of patients with schizophrenia International Clinical Psychopharmacology, April 25, 2013
4 Risperidone, quetiapine, and olanzapine adjunctive treatments in major depression with psychotic features: a comparative study Neuropsychiatric Disease and Treatment, April 18, 2013 Free full text
5 Effectiveness of lurasidone vs. quetiapine XR for relapse prevention in schizophrenia: A 12-month, double-blind, noninferiority study Schizophrenia Research, April 16, 2013
6 A randomized add-on trial of high-dose d -cycloserine for treatment-resistant depression International Journal of Neuropsychopharmacology, March 6, 2013
7 Full central neurokinin-1 receptor blockade is required for efficacy in depression: evidence from orvepitant clinical studies Journal of Psychopharmacology, April 8, 2013
8 The sertraline versus electrical current therapy for treating depression clinical study (SELECT-TDCS): results of the crossover and follow-up phases Depression and Anxiety, April 29, 2013
9 Add-on fluvoxamine treatment for schizophrenia: an updated meta-analysis of randomized controlled trials European Archives of Psychiatry and Clinical Neuroscience, April 22, 2013 Evidence Based Medicine
10 A Randomized Trial on the Acute and Steady-State Effects of a New Antidepressant, Vortioxetine, on Actual Driving and Cognition Clinical Pharmacology & Therapeutics, April 24, 2013
11 Guidance for the Discontinuation or Switching of Antidepressant Therapies in Adults Journal of Pharmacy Practice, March 26, 2013 Clinical Guideline
12 The effect of zonisamide on antipsychotic-associated weight gain in patients with schizophrenia: A randomized, double-blind, placebo-controlled clinical trial Schizophrenia Research, April 17, 2013
13 A randomised, double-blind, placebo-controlled, efficacy study of nalmefene, as-needed use, in patients with alcohol dependence European Neuropsychopharmacology, April 12, 2013
14 Reboxetine Treatment for Autistic Spectrum Disorder of Pediatric Patients With Depressive and Inattentive/Hyperactive Symptoms: An Open-Label Trial Clinical Neuropharmacology, April 5, 2013
15 Efficacy of the novel antidepressant agomelatine for anxiety symptoms in major depression Human Psychopharmacology: Clinical and Experimental, March 28, 2013
16 Additional ECT increases BDNF-levels in patients suffering from major depressive disorders compared to patients treated with citalopram only Journal of Psychiatric Research, April 15, 2013
17
Memantine as adjunctive treatment to risperidone in children with autistic disorder: a randomized, double-blind, placebo-controlled trial
International Journal of Neuropsychopharmacology, April 2, 2013
Exclusive Author Commentary
18 Asenapine effects on individual Young Mania Rating Scale items in bipolar disorder patients with acute manic or mixed episodes: a pooled analysis Neuropsychiatric Disease and Treatment, April 9, 2013 Free full text
19 The Fetal Safety of Fluoxetine: A Systematic Review and Meta-Analysis Journal of Obstetrics and Gynaecology Canada, April 11, 2013 Free full text Evidence Based Medicine Review Article
20 A double-blind, placebo-controlled study of adjunctive calcitonin nasal spray in acute refractory mania Bipolar Disorders, April 2, 2013
Indexed Journals in Psychiatry : Current Psychiatry, Bipolar Disorders, American Journal of Psychiatry, Addiction more
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