MDLinx Psychiatry is your one-stop shop for the peer-reviewed journal articles published in your field. We sort, rank and summarize the literature within 24 hours – hot off the presses! – so you can stay current without drowning in those piles of Current Psychiatry, Bipolar Disorders, and American Journal of Psychiatry. Also find bonus content like clinical pearls from The Smartest Psychiatrist Physician Review and daily quiz competition. Not sure where to start? Skim some of the recent “must read” articles highlighted by our own physician editor D. Scott Cunningham, MD, PhD.
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381 One-year, randomized, open trial comparing olanzapine, quetiapine, risperidone and ziprasidone effectiveness in antipsychotic-naive patients with a first-episode psychosis Psychiatry Research, December 4, 2012 Clinical Article
382 Effects of pioglitazone on metabolic abnormalities, psychopathology, and cognitive function in schizophrenic patients treated with antipsychotic medication: A randomized double-blind study Schizophrenia Research, December 4, 2012 Clinical Article
383 Schizophrenia: Managing Symptoms With Antipsychotics Full Text U.S. Pharmacist, December 4, 2012
384 Cognitive Outcomes After Sertaline Treatment in Patients With Depression of Alzheimer Disease The American Journal of Geriatric Psychiatry, November 30, 2012 Clinical Article
385 Olanzapine and risperidone effects on appetite and ghrelin in chronic schizophrenic patients Psychiatry Research, November 26, 2012 Clinical Article
386 Decreased default network connectivity is associated with early life stress in medication-free healthy adults European Neuropsychopharmacology, November 21, 2012
387 Corticolimbic Brain Reactivity to Social Signals of Threat Before and After Sertraline Treatment in Generalized Social Phobia Biological Psychiatry, November 20, 2012 Clinical Article
388 Achieving and sustaining remission in bipolar I disorder with ziprasidone: apost hocanalysis of a 24-week, double-blind, placebo-controlled study Clinical Drug Investigation, November 19, 2012 Clinical Article
389 A 6 week, randomized, multicentre, open-label study comparing efficacy and tolerability of amisulpride at a starting dose of 400 mg/day versus 800 mg/day in patients with acute exacerbations of schizophrenia Clinical Drug Investigation, November 19, 2012 Clinical Article
390 Danish physicians’ preferences for prescribing escitalopram over citalopram and sertraline to treatment-naïve patients: a national, register-based study European Journal of Clinical Pharmacology, November 19, 2012 Clinical Article
391 Association of Depression and Antidepressant Use with Mortality in a Large Cohort of Patients with Nondialysis-Dependent CKD Clinical Journal of the American Society of Nephrology, November 16, 2012 Clinical Article
392 The Antidepressant Agomelatine in Daily Practice: Results of the Non-Interventional Study VIVALDI Pharmacopsychiatry, November 15, 2012 Clinical Article
393 Effect of modafinil on impulsivity and relapse in alcohol dependent patients: A randomized, placebo-controlled trial European Neuropsychopharmacology, November 15, 2012 Clinical Article
394 Use of varenicline for smoking cessation and risk of serious cardiovascular events: nationwide cohort study British Medical Journal, November 14, 2012 Clinical Article
395 Single ketamine infusion in bipolar depression resistant to antidepressants: are neurotrophins involved? Human Psychopharmacology: Clinical and Experimental, November 9, 2012 Clinical Article
396 Efficacy and metabolic influence of paliperidone ER, aripiprazole and ziprasidone to patients with first-episode schizophrenia through 52weeks follow-up in China Human Psychopharmacology: Clinical and Experimental, November 9, 2012 Clinical Article
397 The efficacy of a topical sialogogue spray containing 1% malic acid in patients with antidepressant-induced dry mouth: a double-blind, randomized clinical trial Depression and Anxiety, November 8, 2012 Clinical Article
398 Randomised, double-blind, placebo-controlled study of olanzapine in patients with bipolar I depression The British Journal of Psychiatry, November 6, 2012 Clinical Article
399 Saliva levels of 3-methoxy-4-hydroxyphenylglycol and clinical efficacy of mirtazapine or selective serotonin reuptake inhibitors in patients with major depression Human Psychopharmacology: Clinical and Experimental, November 6, 2012 Clinical Article
400 Effect of lersivirine co-administration on pharmacokinetics of methadone in healthy volunteers Drug and Alcohol Dependence, November 6, 2012
As published in the American Journal of Obstetrics and Gynecology, risk factors for postpartum depression among abused women included age 15-19 (aOR=2.29) and > 35 years of age (aOR=2.33). In non-abused women, risk factors for postpartum depression include unemployment (aOR=1.41), foreign birth (aOR=2.04), and low income (aOR=1.68). Postpartum depression was also associated with women abused prior to pregnancy (aOR=3.28), abuse beginning postpartum (aOR=4.76), and abuse resuming postpartum (aOR=3.81).
Read the article summaryAs published in the British Journal of Psychiatry, low cardiovascular fitness at 18 years of age (n = 1,117,292; follow-up, 3-40 y) is associated with an increased risk of severe depression (HR = 1.96).
Read the article summaryAs published in Clinical Drug Investigation, an initial amisulpride dose of 800 mg (n=38) is more effective that 400 mg with dose titration (n=30) in patients with an acute exacerbation of schizophrenia. A greater number of patients in the 800 mg group than the 400 mg with dose titration group had a 30% reduction in the Positive and Negative Symptom Scale after 4 (68.4% vs. 40.0%) and 6 weeks (71.1% vs. 43.3%).
Read the article summary1 Nidotherapy for people with schizophrenia Cochrane Reviews, April 11, 2013 Evidence Based Medicine
2 Augmentation with Atypical Antipsychotics for Depression: A Review of Evidence-Based Support from the Medical Literature Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, March 13, 2013 Evidence Based Medicine
3 Long-term safety and tolerability of aripiprazole once-monthly in maintenance treatment of patients with schizophrenia International Clinical Psychopharmacology, April 25, 2013
4 Risperidone, quetiapine, and olanzapine adjunctive treatments in major depression with psychotic features: a comparative study Neuropsychiatric Disease and Treatment, April 18, 2013 Free full text
5 Effectiveness of lurasidone vs. quetiapine XR for relapse prevention in schizophrenia: A 12-month, double-blind, noninferiority study Schizophrenia Research, April 16, 2013
6 A randomized add-on trial of high-dose d -cycloserine for treatment-resistant depression International Journal of Neuropsychopharmacology, March 6, 2013
7 Full central neurokinin-1 receptor blockade is required for efficacy in depression: evidence from orvepitant clinical studies Journal of Psychopharmacology, April 8, 2013
8 The sertraline versus electrical current therapy for treating depression clinical study (SELECT-TDCS): results of the crossover and follow-up phases Depression and Anxiety, April 29, 2013
9 Add-on fluvoxamine treatment for schizophrenia: an updated meta-analysis of randomized controlled trials European Archives of Psychiatry and Clinical Neuroscience, April 22, 2013 Evidence Based Medicine
10 A Randomized Trial on the Acute and Steady-State Effects of a New Antidepressant, Vortioxetine, on Actual Driving and Cognition Clinical Pharmacology & Therapeutics, April 24, 2013
11 Guidance for the Discontinuation or Switching of Antidepressant Therapies in Adults Journal of Pharmacy Practice, March 26, 2013 Clinical Guideline
12 The effect of zonisamide on antipsychotic-associated weight gain in patients with schizophrenia: A randomized, double-blind, placebo-controlled clinical trial Schizophrenia Research, April 17, 2013
13 A randomised, double-blind, placebo-controlled, efficacy study of nalmefene, as-needed use, in patients with alcohol dependence European Neuropsychopharmacology, April 12, 2013
14 Reboxetine Treatment for Autistic Spectrum Disorder of Pediatric Patients With Depressive and Inattentive/Hyperactive Symptoms: An Open-Label Trial Clinical Neuropharmacology, April 5, 2013
15 Efficacy of the novel antidepressant agomelatine for anxiety symptoms in major depression Human Psychopharmacology: Clinical and Experimental, March 28, 2013
16 Additional ECT increases BDNF-levels in patients suffering from major depressive disorders compared to patients treated with citalopram only Journal of Psychiatric Research, April 15, 2013
17
Memantine as adjunctive treatment to risperidone in children with autistic disorder: a randomized, double-blind, placebo-controlled trial
International Journal of Neuropsychopharmacology, April 2, 2013
Exclusive Author Commentary
18 Asenapine effects on individual Young Mania Rating Scale items in bipolar disorder patients with acute manic or mixed episodes: a pooled analysis Neuropsychiatric Disease and Treatment, April 9, 2013 Free full text
19 The Fetal Safety of Fluoxetine: A Systematic Review and Meta-Analysis Journal of Obstetrics and Gynaecology Canada, April 11, 2013 Free full text Evidence Based Medicine Review Article
20 A double-blind, placebo-controlled study of adjunctive calcitonin nasal spray in acute refractory mania Bipolar Disorders, April 2, 2013
Indexed Journals in Psychiatry : Current Psychiatry, Bipolar Disorders, American Journal of Psychiatry, Addiction more
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