Risk factors for suicidal ideations in bipolar disorder
As reported in Bipolar Disorders, the following risk factors were associated with suicidal ideations in patients with bipolar disorder (n=130): grade of severity of current episode (OR=22.601); family history of suicide attempt (OR=18.06); preceding life event (OR=3.797); and past history of suicidal event (OR=3.11).
Asenapine effective in treating agitation
As reported in Acta Psychiatrica Scandinavica, treatment of agitation with sublingual asenapine (10 mg) was shown to be effective. Improvement in the PANSS-EC was comparable to the effect of intramuscular anti-psychotics.
Elderly depressed patients at increased risk for metabolic syndrome and elevated CRP
As reported in Psychosomatics, of 30 patients with newly diagnosed depression, the risk for metabolic syndrome (OR=4.75 [waist circumference OR=6.00]) and CRP (OR=3.86) was increased.