Predictors of quality of life in inpatients with schizophrenia
Psychiatry Research, 08/17/2012
Fujimaki K et al. – This study shows that active treatment for negative symptoms, psychological discomfort, and resistance should be recommended to improve quality of life (QOL) among inpatients with schizophrenia.Methods
- The study sample consisted of 217 inpatients with schizophrenia.
- Age, duration of illness, duration of hospitalization, years of education, body mass index, neurocognitive function, drug-induced extrapyramidal symptoms, involuntary movements, psychiatric symptoms, and dose equivalents of antipsychotics and anticholinergic agents were used as index factors.
- Pearson linear correlation and regression analyses were performed to examine the associations between QOL and the above-mentioned factors.
- Negative symptoms, psychological discomfort, and resistance as rated on the Brief Psychiatric Rating Scale (BPRS) were correlated with all subscale scores of the Japanese version of the Schizophrenia Quality of Life Scale (JSQLS).
- Stepwise regression showed that negative symptoms, psychological discomfort, and resistance predicted the dysfunction of psycho-social activity score and the dysfunction of motivation and energy score on the JSQLS.