Emotion processing and regulation in bipolar disorder: a review

Bipolar Disorders, 06/12/2012

The investigations reveal that amygdala activation varies as a function of mood state, while the prefrontal cortex (PFC) remains persistently hypoactivated across mood states. Emotional dysregulation and lability in mania and depression may reflect disruption of a frontal–limbic functional neuroanatomical network.

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