A Randomized Controlled Trial of CBT Therapy for Adults with ADHD with and without Medication Full Text
BMC Psychiatry, 04/10/2012
Clinical Article
Weiss M et al. – This study replicates previous work demonstrating that CBT is an effective treatment for ADHD in adults. Within the limits of this pilot, secondary analysis the authors were not able to demonstrate that medication significantly augments the outcome of CBT therapy for adults with ADHD.
Methods- This was a secondary analysis comparing 23 participants randomized to CBT and Dectroamphetamine vs. 25 participants randomized to CBT and placebo.
- Both patients and investigators were blind to treatment assignment.
- Two co-primary outcomes were used: ADHD symptoms on the ADHD-RS-Inv completed by the investigator and improvement in functioning as reported by the patient on the Sheehan Disability Scale.
- Both groups showed robust improvement in both symptoms and functioning, but the use of medication did not significantly improve outcome over and above use of CBT and placebo.



