Stressful life events at onset of obsessive-compulsive disorder are associated with a distinct clinical pattern
Depression and Anxiety, 02/17/2011
Real E et al. –The aim of this study was to establish whether OCD preceded by a stressful life event (SLE) presents a different clinical pattern compared to non-SLE-preceded OCD. Patients with OCD onset close to an SLE and those without an SLE close to OCD onset show a distinct clinical pattern.Methods
- Interviewed 412 OCD patients to assess both SLEs at onset of OCD and other clinical variables, including OCD symptom dimensions.
- Logistic regression applied to explore relationship between clinical variables and OCD preceded by an SLE
- SLE-preceded OCD group showed later onset of disorder (OR = 1.04, P = .015),history of complicated birth (OR = 5.54, P<.001), less family history of OCD (OR = 0.42, P = .014), and presence of contamination/cleaning symptoms (OR = 1.99, P = .01)